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Preclinical PET Study of Intravitreal Injections.
Fernández-Ferreiro A, Luaces-Rodríguez A, Aguiar P, Pardo-Montero J, González-Barcia M, García-Varela L, Herranz M, Silva-Rodríguez J, Gil-Martínez M, Bermúdez MA, Vieites-Prado A, Blanco-Méndez J, Lamas MJ, Gómez-Ulla F, Ruibal Á, Otero-Espinar FJ, González F. Fernández-Ferreiro A, et al. Invest Ophthalmol Vis Sci. 2017 Jun 1;58(7):2843-2851. doi: 10.1167/iovs.17-21812. Invest Ophthalmol Vis Sci. 2017. PMID: 28570736
Positron Emission Tomography for the Development and Characterization of Corneal Permanence of Ophthalmic Pharmaceutical Formulations.
Fernández-Ferreiro A, Silva-Rodríguez J, Otero-Espinar FJ, González-Barcia M, Lamas MJ, Ruibal A, Luaces-Rodriguez A, Vieites-Prado A, Sobrino T, Herranz M, García-Varela L, Blanco-Mendez J, Gil-Martínez M, Pardo M, Moscoso A, Medín-Aguerre S, Pardo-Montero J, Aguiar P. Fernández-Ferreiro A, et al. Invest Ophthalmol Vis Sci. 2017 Feb 1;58(2):772-780. doi: 10.1167/iovs.16-20766. Invest Ophthalmol Vis Sci. 2017. PMID: 28146242
Vaginal residence and pharmacokinetic preclinical study of topical vaginal mucoadhesive W/S emulsions containing ciprofloxacin.
Campaña-Seoane M, Pérez-Gago A, Vázquez G, Conde N, González P, Martinez A, Martínez X, García Varela L, Herranz M, Aguiar P, Fernández-Ferreiro A, Laguna R, Otero-Espinar FJ. Campaña-Seoane M, et al. Int J Pharm. 2019 Jan 10;554:276-283. doi: 10.1016/j.ijpharm.2018.11.022. Epub 2018 Nov 10. Int J Pharm. 2019. PMID: 30423417
Test-Retest Repeatability of [18F]MC225-PET in Rodents: A Tracer for Imaging of P-gp Function.
García-Varela L, Vállez García D, Rodríguez-Pérez M, van Waarde A, Sijbesma JWA, Schildt A, Kwizera C, Aguiar P, Sobrino T, Dierckx RAJO, Elsinga PH, Luurtsema G. García-Varela L, et al. ACS Chem Neurosci. 2020 Feb 19;11(4):648-658. doi: 10.1021/acschemneuro.9b00682. Epub 2020 Feb 3. ACS Chem Neurosci. 2020. PMID: 31961646 Free PMC article.
[18F]-FMISO PET/MRI Imaging Shows Ischemic Tissue around Hematoma in Intracerebral Hemorrhage.
Gómez-Lado N, López-Arias E, Iglesias-Rey R, Díaz-Platas L, Medín-Aguerre S, Fernández-Ferreiro A, Posado-Fernández A, García-Varela L, Rodríguez-Pérez M, Campos F, Del Pino P, Ruibal Á, Pardo-Montero J, Castillo J, Aguiar P, Sobrino T. Gómez-Lado N, et al. Mol Pharm. 2020 Dec 7;17(12):4667-4675. doi: 10.1021/acs.molpharmaceut.0c00932. Epub 2020 Nov 13. Mol Pharm. 2020. PMID: 33186043
Head-to-head comparison of (R)-[11C]verapamil and [18F]MC225 in non-human primates, tracers for measuring P-glycoprotein function.
García-Varela L, Vállez García D, Aguiar P, Kakiuchi T, Ohba H, Harada N, Nishiyama S, Tago T, Elsinga PH, Tsukada H, Colabufo NA, Dierckx RAJO, van Waarde A, Toyohara J, Boellaard R, Luurtsema G. García-Varela L, et al. Eur J Nucl Med Mol Imaging. 2021 Dec;48(13):4307-4317. doi: 10.1007/s00259-021-05411-2. Epub 2021 Jun 11. Eur J Nucl Med Mol Imaging. 2021. PMID: 34117508 Free PMC article.
In Vivo Induction of P-Glycoprotein Function can be Measured with [18F]MC225 and PET.
García-Varela L, Rodríguez-Pérez M, Custodia A, Moraga-Amaro R, Colabufo NA, Aguiar P, Sobrino T, Dierckx RAJO, van Waarde A, Elsinga PH, Luurtsema G. García-Varela L, et al. Mol Pharm. 2021 Aug 2;18(8):3073-3085. doi: 10.1021/acs.molpharmaceut.1c00302. Epub 2021 Jul 6. Mol Pharm. 2021. PMID: 34228458 Free PMC article.
19 results