García-Tuñón I - Search Results

1

CRISPR/Cas9-Directed Gene Trap Constitutes a Selection System for Corrected BCR/ABL Leukemic Cells in CML.

Vuelta E, Ordoñez JL, Sanz DJ, Ballesteros S, Hernández-Rivas JM, Méndez-Sánchez L, Sánchez-Martín M, García-Tuñón I. Vuelta E, et al. Among authors: garcia tunon i. Int J Mol Sci. 2022 Jun 7;23(12):6386. doi: 10.3390/ijms23126386. Int J Mol Sci. 2022. PMID: 35742831 Free PMC article.

2

Understanding HAT1: A Comprehensive Review of Noncanonical Roles and Connection with Disease.

Ortega MA, De Leon-Oliva D, Garcia-Montero C, Fraile-Martinez O, Boaru DL, Del Val Toledo Lobo M, García-Tuñón I, Royuela M, García-Honduvilla N, Bujan J, Guijarro LG, Alvarez-Mon M, Alvarez-Mon MÁ. Ortega MA, et al. Among authors: garcia tunon i. Genes (Basel). 2023 Apr 14;14(4):915. doi: 10.3390/genes14040915. Genes (Basel). 2023. PMID: 37107673 Free PMC article. Review.

3

Meiotic cohesin complexes are essential for the formation of the axial element in mice.

Llano E, Herrán Y, García-Tuñón I, Gutiérrez-Caballero C, de Álava E, Barbero JL, Schimenti J, de Rooij DG, Sánchez-Martín M, Pendás AM. Llano E, et al. J Cell Biol. 2012 Jun 25;197(7):877-85. doi: 10.1083/jcb.201201100. Epub 2012 Jun 18. J Cell Biol. 2012. PMID: 22711701 Free PMC article.

4

STAG3 is a strong candidate gene for male infertility.

Llano E, Gomez-H L, García-Tuñón I, Sánchez-Martín M, Caburet S, Barbero JL, Schimenti JC, Veitia RA, Pendas AM. Llano E, et al. Hum Mol Genet. 2014 Jul 1;23(13):3421-31. doi: 10.1093/hmg/ddu051. Epub 2014 Mar 7. Hum Mol Genet. 2014. PMID: 24608227 Free article.

5

C14ORF39/SIX6OS1 is a constituent of the synaptonemal complex and is essential for mouse fertility.

Gómez-H L, Felipe-Medina N, Sánchez-Martín M, Davies OR, Ramos I, García-Tuñón I, de Rooij DG, Dereli I, Tóth A, Barbero JL, Benavente R, Llano E, Pendas AM. Gómez-H L, et al. Nat Commun. 2016 Oct 31;7:13298. doi: 10.1038/ncomms13298. Nat Commun. 2016. PMID: 27796301 Free PMC article.

6

The CRISPR/Cas9 system efficiently reverts the tumorigenic ability of BCR/ABL in vitro and in a xenograft model of chronic myeloid leukemia.

García-Tuñón I, Hernández-Sánchez M, Ordoñez JL, Alonso-Pérez V, Álamo-Quijada M, Benito R, Guerrero C, Hernández-Rivas JM, Sánchez-Martín M. García-Tuñón I, et al. Oncotarget. 2017 Apr 18;8(16):26027-26040. doi: 10.18632/oncotarget.15215. Oncotarget. 2017. PMID: 28212528 Free PMC article.

7

Splice donor site sgRNAs enhance CRISPR/Cas9-mediated knockout efficiency.

García-Tuñón I, Alonso-Pérez V, Vuelta E, Pérez-Ramos S, Herrero M, Méndez L, Hernández-Sánchez JM, Martín-Izquierdo M, Saldaña R, Sevilla J, Sánchez-Guijo F, Hernández-Rivas JM, Sánchez-Martín M. García-Tuñón I, et al. PLoS One. 2019 May 9;14(5):e0216674. doi: 10.1371/journal.pone.0216674. eCollection 2019. PLoS One. 2019. PMID: 31071190 Free PMC article.

8

Establishment of a conditional Nomo1 mouse model by CRISPR/Cas9 technology.

García-Tuñón I, Vuelta E, Lozano L, Herrero M, Méndez L, Palomero-Hernandez J, Pérez-Caro M, Pérez-García J, González-Sarmiento R, Sánchez-Martín M. García-Tuñón I, et al. Mol Biol Rep. 2020 Feb;47(2):1381-1391. doi: 10.1007/s11033-019-05214-7. Epub 2019 Dec 12. Mol Biol Rep. 2020. PMID: 31833031

9

Cyba-deficient mice display an increase in hematopoietic stem cells and an overproduction of immunoglobulins.

Prieto-Bermejo R, Romo-González M, Pérez-Fernández A, García-Tuñón I, Sánchez-Martín M, Hernández-Hernández Á. Prieto-Bermejo R, et al. Haematologica. 2021 Jan 1;106(1):142-153. doi: 10.3324/haematol.2019.233064. Haematologica. 2021. PMID: 31919083 Free PMC article.

10

ETV6/RUNX1 Fusion Gene Abrogation Decreases the Oncogenicity of Tumour Cells in a Preclinical Model of Acute Lymphoblastic Leukaemia.

Montaño A, Ordoñez JL, Alonso-Pérez V, Hernández-Sánchez J, Santos S, González T, Benito R, García-Tuñón I, Hernández-Rivas JM. Montaño A, et al. Cells. 2020 Jan 15;9(1):215. doi: 10.3390/cells9010215. Cells. 2020. PMID: 31952221 Free PMC article.

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