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Page 1
Targeted genome editing in acute lymphoblastic leukemia: a review.
Montaño A, Forero-Castro M, Hernández-Rivas JM, García-Tuñón I, Benito R. Montaño A, et al. BMC Biotechnol. 2018 Jul 17;18(1):45. doi: 10.1186/s12896-018-0455-9. BMC Biotechnol. 2018. PMID: 30016959 Free PMC article. Review.
Understanding HAT1: A Comprehensive Review of Noncanonical Roles and Connection with Disease.
Ortega MA, De Leon-Oliva D, Garcia-Montero C, Fraile-Martinez O, Boaru DL, Del Val Toledo Lobo M, García-Tuñón I, Royuela M, García-Honduvilla N, Bujan J, Guijarro LG, Alvarez-Mon M, Alvarez-Mon MÁ. Ortega MA, et al. Among authors: garcia tunon i. Genes (Basel). 2023 Apr 14;14(4):915. doi: 10.3390/genes14040915. Genes (Basel). 2023. PMID: 37107673 Free PMC article. Review.
CRISPR/Cas9-generated models uncover therapeutic vulnerabilities of del(11q) CLL cells to dual BCR and PARP inhibition.
Quijada-Álamo M, Hernández-Sánchez M, Alonso-Pérez V, Rodríguez-Vicente AE, García-Tuñón I, Martín-Izquierdo M, Hernández-Sánchez JM, Herrero AB, Bastida JM, San Segundo L, Gruber M, García JL, Yin S, Ten Hacken E, Benito R, Ordóñez JL, Wu CJ, Hernández-Rivas JM. Quijada-Álamo M, et al. Leukemia. 2020 Jun;34(6):1599-1612. doi: 10.1038/s41375-020-0714-3. Epub 2020 Jan 23. Leukemia. 2020. PMID: 31974435 Free PMC article.
Characterization of the Platelet Phenotype Caused by a Germline RUNX1 Variant in a CRISPR/Cas9-Generated Murine Model.
Marín-Quílez A, García-Tuñón I, Fernández-Infante C, Hernández-Cano L, Palma-Barqueros V, Vuelta E, Sánchez-Martín M, González-Porras JR, Guerrero C, Benito R, Rivera J, Hernández-Rivas JM, Bastida JM. Marín-Quílez A, et al. Thromb Haemost. 2021 Sep;121(9):1193-1205. doi: 10.1055/s-0041-1723987. Epub 2021 Feb 18. Thromb Haemost. 2021. PMID: 33626581
Biological significance of monoallelic and biallelic BIRC3 loss in del(11q) chronic lymphocytic leukemia progression.
Quijada-Álamo M, Hernández-Sánchez M, Rodríguez-Vicente AE, Pérez-Carretero C, Rodríguez-Sánchez A, Martín-Izquierdo M, Alonso-Pérez V, García-Tuñón I, Bastida JM, Vidal-Manceñido MJ, Galende J, Aguilar C, Queizán JA, González-Gascón Y Marín I, Hernández-Rivas JÁ, Benito R, Ordóñez JL, Hernández-Rivas JM. Quijada-Álamo M, et al. Among authors: garcia tunon i. Blood Cancer J. 2021 Jul 9;11(7):127. doi: 10.1038/s41408-021-00520-5. Blood Cancer J. 2021. PMID: 34244476 Free PMC article.
A novel nonsense variant in TPM4 caused dominant macrothrombocytopenia, mild bleeding tendency and disrupted cytoskeleton remodeling.
Marín-Quílez A, Vuelta E, Díaz-Ajenjo L, Fernández-Infante C, García-Tuñón I, Benito R, Palma-Barqueros V, Hernández-Rivas JM, González-Porras JR, Rivera J, Bastida JM. Marín-Quílez A, et al. Among authors: garcia tunon i. J Thromb Haemost. 2022 May;20(5):1248-1255. doi: 10.1111/jth.15672. Epub 2022 Feb 28. J Thromb Haemost. 2022. PMID: 35170221 Free PMC article.
Novel variants in GALE cause syndromic macrothrombocytopenia by disrupting glycosylation and thrombopoiesis.
Marín-Quílez A, Di Buduo CA, Díaz-Ajenjo L, Abbonante V, Vuelta E, Soprano PM, Miguel-García C, Santos-Mínguez S, Serramito-Gómez I, Ruiz-Sala P, Peñarrubia MJ, Pardal E, Hernández-Rivas JM, González-Porras JR, García-Tuñón I, Benito R, Rivera J, Balduini A, Bastida JM. Marín-Quílez A, et al. Among authors: garcia tunon i. Blood. 2023 Jan 26;141(4):406-421. doi: 10.1182/blood.2022016995. Blood. 2023. PMID: 36395340 Free PMC article.
Splice donor site sgRNAs enhance CRISPR/Cas9-mediated knockout efficiency.
García-Tuñón I, Alonso-Pérez V, Vuelta E, Pérez-Ramos S, Herrero M, Méndez L, Hernández-Sánchez JM, Martín-Izquierdo M, Saldaña R, Sevilla J, Sánchez-Guijo F, Hernández-Rivas JM, Sánchez-Martín M. García-Tuñón I, et al. PLoS One. 2019 May 9;14(5):e0216674. doi: 10.1371/journal.pone.0216674. eCollection 2019. PLoS One. 2019. PMID: 31071190 Free PMC article.
45 results