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Orally administered Odoribacter laneus improves glucose control and inflammatory profile in obese mice by depleting circulating succinate.
Huber-Ruano I, Calvo E, Mayneris-Perxachs J, Rodríguez-Peña MM, Ceperuelo-Mallafré V, Cedó L, Núñez-Roa C, Miro-Blanch J, Arnoriaga-Rodríguez M, Balvay A, Maudet C, García-Roves P, Yanes O, Rabot S, Grimaud GM, De Prisco A, Amoruso A, Fernández-Real JM, Vendrell J, Fernández-Veledo S. Huber-Ruano I, et al. Among authors: garcia roves p. Microbiome. 2022 Aug 25;10(1):135. doi: 10.1186/s40168-022-01306-y. Microbiome. 2022. PMID: 36002880 Free PMC article.
Adipose tissue glycogen accumulation is associated with obesity-linked inflammation in humans.
Ceperuelo-Mallafré V, Ejarque M, Serena C, Duran X, Montori-Grau M, Rodríguez MA, Yanes O, Núñez-Roa C, Roche K, Puthanveetil P, Garrido-Sánchez L, Saez E, Tinahones FJ, Garcia-Roves PM, Gómez-Foix AM, Saltiel AR, Vendrell J, Fernández-Veledo S. Ceperuelo-Mallafré V, et al. Mol Metab. 2015 Oct 16;5(1):5-18. doi: 10.1016/j.molmet.2015.10.001. eCollection 2016 Jan. Mol Metab. 2015. PMID: 26844203 Free PMC article.
Remission of obesity and insulin resistance is not sufficient to restore mitochondrial homeostasis in visceral adipose tissue.
Gonzalez-Franquesa A, Gama-Perez P, Kulis M, Szczepanowska K, Dahdah N, Moreno-Gomez S, Latorre-Pellicer A, Fernández-Ruiz R, Aguilar-Mogas A, Hoffman A, Monelli E, Samino S, Miró-Blanch J, Oemer G, Duran X, Sanchez-Rebordelo E, Schneeberger M, Obach M, Montane J, Castellano G, Chapaprieta V, Sun W, Navarro L, Prieto I, Castaño C, Novials A, Gomis R, Monsalve M, Claret M, Graupera M, Soria G, Wolfrum C, Vendrell J, Fernández-Veledo S, Enríquez JA, Carracedo A, Perales JC, Nogueiras R, Herrero L, Trifunovic A, Keller MA, Yanes O, Sales-Pardo M, Guimerà R, Blüher M, Martín-Subero JI, Garcia-Roves PM. Gonzalez-Franquesa A, et al. Among authors: garcia roves pm. Redox Biol. 2022 Aug;54:102353. doi: 10.1016/j.redox.2022.102353. Epub 2022 Jun 24. Redox Biol. 2022. PMID: 35777200 Free PMC article.
Adipose tissue mitochondrial dysfunction in human obesity is linked to a specific DNA methylation signature in adipose-derived stem cells.
Ejarque M, Ceperuelo-Mallafré V, Serena C, Maymo-Masip E, Duran X, Díaz-Ramos A, Millan-Scheiding M, Núñez-Álvarez Y, Núñez-Roa C, Gama P, Garcia-Roves PM, Peinado MA, Gimble JM, Zorzano A, Vendrell J, Fernández-Veledo S. Ejarque M, et al. Int J Obes (Lond). 2019 Jun;43(6):1256-1268. doi: 10.1038/s41366-018-0219-6. Epub 2018 Sep 27. Int J Obes (Lond). 2019. PMID: 30262812 Free PMC article.
Dietary Betaine Supplementation Increases Fgf21 Levels to Improve Glucose Homeostasis and Reduce Hepatic Lipid Accumulation in Mice.
Ejaz A, Martinez-Guino L, Goldfine AB, Ribas-Aulinas F, De Nigris V, Ribó S, Gonzalez-Franquesa A, Garcia-Roves PM, Li E, Dreyfuss JM, Gall W, Kim JK, Bottiglieri T, Villarroya F, Gerszten RE, Patti ME, Lerin C. Ejaz A, et al. Diabetes. 2016 Apr;65(4):902-12. doi: 10.2337/db15-1094. Epub 2016 Feb 8. Diabetes. 2016. PMID: 26858359 Free PMC article.
Angiocrine polyamine production regulates adiposity.
Monelli E, Villacampa P, Zabala-Letona A, Martinez-Romero A, Llena J, Beiroa D, Gouveia L, Chivite I, Zagmutt S, Gama-Perez P, Osorio-Conles O, Muixi L, Martinez-Gonzalez A, Castillo SD, Martín-Martín N, Castel P, Valcarcel-Jimenez L, Garcia-Gonzalez I, Villena JA, Fernandez-Ruiz S, Serra D, Herrero L, Benedito R, Garcia-Roves P, Vidal J, Cohen P, Nogueiras R, Claret M, Carracedo A, Graupera M. Monelli E, et al. Nat Metab. 2022 Mar;4(3):327-343. doi: 10.1038/s42255-022-00544-6. Epub 2022 Mar 14. Nat Metab. 2022. PMID: 35288722
MacroH2A1.1 regulates mitochondrial respiration by limiting nuclear NAD+ consumption.
Posavec Marjanović M, Hurtado-Bagès S, Lassi M, Valero V, Malinverni R, Delage H, Navarro M, Corujo D, Guberovic I, Douet J, Gama-Perez P, Garcia-Roves PM, Ahel I, Ladurner AG, Yanes O, Bouvet P, Suelves M, Teperino R, Pospisilik JA, Buschbeck M. Posavec Marjanović M, et al. Nat Struct Mol Biol. 2017 Nov;24(11):902-910. doi: 10.1038/nsmb.3481. Epub 2017 Oct 9. Nat Struct Mol Biol. 2017. PMID: 28991266 Free PMC article.
76 results