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Integration of advanced methods and models to study drug absorption and related processes: An UNGAP perspective.
Wilson CG, Aarons L, Augustijns P, Brouwers J, Darwich AS, De Waal T, Garbacz G, Hansmann S, Hoc D, Ivanova A, Koziolek M, Reppas C, Schick P, Vertzoni M, García-Horsman JA. Wilson CG, et al. Among authors: garcia horsman ja. Eur J Pharm Sci. 2022 May 1;172:106100. doi: 10.1016/j.ejps.2021.106100. Epub 2021 Dec 20. Eur J Pharm Sci. 2022. PMID: 34936937 Free article.
Alteration of prolyl oligopeptidase and activated α-2-macroglobulin in multiple sclerosis subtypes and in the clinically isolated syndrome.
Tenorio-Laranga J, Peltonen I, Keskitalo S, Duran-Torres G, Natarajan R, Männistö PT, Nurmi A, Vartiainen N, Airas L, Elovaara I, García-Horsman JA. Tenorio-Laranga J, et al. Among authors: garcia horsman ja. Biochem Pharmacol. 2013 Jun 15;85(12):1783-94. doi: 10.1016/j.bcp.2013.04.018. Epub 2013 Apr 30. Biochem Pharmacol. 2013. PMID: 23643808
Deficiency of prolyl oligopeptidase in mice disturbs synaptic plasticity and reduces anxiety-like behaviour, body weight, and brain volume.
Höfling C, Kulesskaya N, Jaako K, Peltonen I, Männistö PT, Nurmi A, Vartiainen N, Morawski M, Zharkovsky A, Võikar V, Roßner S, García-Horsman JA. Höfling C, et al. Among authors: garcia horsman ja. Eur Neuropsychopharmacol. 2016 Jun;26(6):1048-61. doi: 10.1016/j.euroneuro.2016.02.015. Epub 2016 Feb 27. Eur Neuropsychopharmacol. 2016. PMID: 26996375
The expression levels of prolyl oligopeptidase responds not only to neuroinflammation but also to systemic inflammation upon liver failure in rat models and cirrhotic patients.
Tenorio-Laranga J, Montoliu C, Urios A, Hernandez-Rabaza V, Ahabrach H, García-Horsman JA, Felipo V. Tenorio-Laranga J, et al. Among authors: garcia horsman ja. J Neuroinflammation. 2015 Sep 30;12:183. doi: 10.1186/s12974-015-0404-7. J Neuroinflammation. 2015. PMID: 26420028 Free PMC article.
Synthesis and biological evaluation of novel (123)I-labeled 4-(4-iodophenyl)butanoyl-L-prolyl-(2S)-pyrrolidines for imaging prolyl oligopeptidase in vivo.
Kallinen A, Todorov B, Kallionpää R, Bäck S, Sarparanta M, Raki M, García-Horsman JA, Bergström KA, Wallén EA, Männistö PT, Airaksinen AJ. Kallinen A, et al. Among authors: garcia horsman ja. Eur J Med Chem. 2014 May 22;79:436-45. doi: 10.1016/j.ejmech.2014.04.014. Epub 2014 Apr 12. Eur J Med Chem. 2014. PMID: 24763264
53 results