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Hypothalamic astrocytes control systemic glucose metabolism and energy balance.
Herrera Moro Chao D, Kirchner MK, Pham C, Foppen E, Denis RGP, Castel J, Morel C, Montalban E, Hassouna R, Bui LC, Renault J, Mouffle C, García-Cáceres C, Tschöp MH, Li D, Martin C, Stern JE, Luquet SH. Herrera Moro Chao D, et al. Cell Metab. 2022 Oct 4;34(10):1532-1547.e6. doi: 10.1016/j.cmet.2022.09.002. Cell Metab. 2022. PMID: 36198294 Free PMC article.
Targeted estrogen delivery reverses the metabolic syndrome.
Finan B, Yang B, Ottaway N, Stemmer K, Müller TD, Yi CX, Habegger K, Schriever SC, García-Cáceres C, Kabra DG, Hembree J, Holland J, Raver C, Seeley RJ, Hans W, Irmler M, Beckers J, de Angelis MH, Tiano JP, Mauvais-Jarvis F, Perez-Tilve D, Pfluger P, Zhang L, Gelfanov V, DiMarchi RD, Tschöp MH. Finan B, et al. Nat Med. 2012 Dec;18(12):1847-56. doi: 10.1038/nm.3009. Epub 2012 Nov 11. Nat Med. 2012. PMID: 23142820 Free PMC article.
Hypothalamic astrocytes in obesity.
García-Cáceres C, Yi CX, Tschöp MH. García-Cáceres C, et al. Endocrinol Metab Clin North Am. 2013 Mar;42(1):57-66. doi: 10.1016/j.ecl.2012.11.003. Epub 2012 Dec 12. Endocrinol Metab Clin North Am. 2013. PMID: 23391239 Review.
Estrogen, astrocytes and the neuroendocrine control of metabolism.
Fuente-Martin E, Garcia-Caceres C, Morselli E, Clegg DJ, Chowen JA, Finan B, Brinton RD, Tschöp MH. Fuente-Martin E, et al. Rev Endocr Metab Disord. 2013 Dec;14(4):331-8. doi: 10.1007/s11154-013-9263-7. Rev Endocr Metab Disord. 2013. PMID: 24009071 Free PMC article. Review.
Hormones and diet, but not body weight, control hypothalamic microglial activity.
Gao Y, Ottaway N, Schriever SC, Legutko B, García-Cáceres C, de la Fuente E, Mergen C, Bour S, Thaler JP, Seeley RJ, Filosa J, Stern JE, Perez-Tilve D, Schwartz MW, Tschöp MH, Yi CX. Gao Y, et al. Glia. 2014 Jan;62(1):17-25. doi: 10.1002/glia.22580. Epub 2013 Oct 28. Glia. 2014. PMID: 24166765 Free PMC article.
The emerging neurobiology of calorie addiction.
García-Cáceres C, Tschöp MH. García-Cáceres C, et al. Elife. 2014;3:e01928. doi: 10.7554/eLife.01928. Epub 2014 Jan 7. Elife. 2014. PMID: 24399459 Free PMC article.
Leptin signaling in astrocytes regulates hypothalamic neuronal circuits and feeding.
Kim JG, Suyama S, Koch M, Jin S, Argente-Arizon P, Argente J, Liu ZW, Zimmer MR, Jeong JK, Szigeti-Buck K, Gao Y, Garcia-Caceres C, Yi CX, Salmaso N, Vaccarino FM, Chowen J, Diano S, Dietrich MO, Tschöp MH, Horvath TL. Kim JG, et al. Nat Neurosci. 2014 Jul;17(7):908-10. doi: 10.1038/nn.3725. Epub 2014 Jun 1. Nat Neurosci. 2014. PMID: 24880214 Free PMC article.
Hypothalamic PGC-1α protects against high-fat diet exposure by regulating ERα.
Morselli E, Fuente-Martin E, Finan B, Kim M, Frank A, Garcia-Caceres C, Navas CR, Gordillo R, Neinast M, Kalainayakan SP, Li DL, Gao Y, Yi CX, Hahner L, Palmer BF, Tschöp MH, Clegg DJ. Morselli E, et al. Cell Rep. 2014 Oct 23;9(2):633-45. doi: 10.1016/j.celrep.2014.09.025. Epub 2014 Oct 16. Cell Rep. 2014. PMID: 25373903 Free PMC article.
Hypothalamic Injury: Fish Oil to the Rescue!
García-Cáceres C, Tschöp MH. García-Cáceres C, et al. Diabetes. 2016 Mar;65(3):551-3. doi: 10.2337/dbi15-0036. Diabetes. 2016. PMID: 26908906 No abstract available.
Hypothalamic leptin action is mediated by histone deacetylase 5.
Kabra DG, Pfuhlmann K, García-Cáceres C, Schriever SC, Casquero García V, Kebede AF, Fuente-Martin E, Trivedi C, Heppner K, Uhlenhaut NH, Legutko B, Kabra UD, Gao Y, Yi CX, Quarta C, Clemmensen C, Finan B, Müller TD, Meyer CW, Paez-Pereda M, Stemmer K, Woods SC, Perez-Tilve D, Schneider R, Olson EN, Tschöp MH, Pfluger PT. Kabra DG, et al. Nat Commun. 2016 Feb 29;7:10782. doi: 10.1038/ncomms10782. Nat Commun. 2016. PMID: 26923837 Free PMC article.
72 results