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Anti-inflammatory effect and inhibition of nitric oxide production by targeting COXs and iNOS enzymes with the 1,2-diphenylbenzimidazole pharmacophore.
Bioorg Med Chem. 2020 May 1;28(9):115427. doi: 10.1016/j.bmc.2020.115427. Epub 2020 Mar 21.
Bioorg Med Chem. 2020.
PMID: 32205045
Involvement of conformational isomerism in the complexity of the crystal network of 1-(4-nitrophenyl)-1H-1,3-benzimidazole derivatives driven by C-H...A (A = NO2, Npy and π) and orthogonal Npy...NO2 and ONO...Csp2 interactions.
García-Aranda MI, Gómez-Castro CZ, García-Báez EV, Gómez YGY, Castrejón-Flores JL, Padilla-Martínez II.
García-Aranda MI, et al.
Acta Crystallogr C Struct Chem. 2018 Apr 1;74(Pt 4):428-436. doi: 10.1107/S2053229618003406. Epub 2018 Mar 7.
Acta Crystallogr C Struct Chem. 2018.
PMID: 29620026
Free PMC article.
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Helical peptides from VEGF and Vammin hotspots for modulating the VEGF-VEGFR interaction.
García-Aranda MI, González-López S, Santiveri CM, Gagey-Eilstein N, Reille-Seroussi M, Martín-Martínez M, Inguimbert N, Vidal M, García-López MT, Jiménez MA, González-Muñiz R, Pérez de Vega MJ.
García-Aranda MI, et al.
Org Biomol Chem. 2013 Mar 21;11(11):1896-905. doi: 10.1039/c3ob27312a. Epub 2013 Feb 4.
Org Biomol Chem. 2013.
PMID: 23381088
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Disulfide and amide-bridged cyclic peptide analogues of the VEGF₈₁₋₉₁ fragment: synthesis, conformational analysis and biological evaluation.
García-Aranda MI, Mirassou Y, Gautier B, Martín-Martínez M, Inguimbert N, Vidal M, García-López MT, Jiménez MA, González-Muñiz R, Pérez de Vega MJ.
García-Aranda MI, et al.
Bioorg Med Chem. 2011 Dec 15;19(24):7526-33. doi: 10.1016/j.bmc.2011.10.032. Epub 2011 Oct 18.
Bioorg Med Chem. 2011.
PMID: 22078412
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Parallel solid-phase synthesis of a small library of linear and hydrocarbon-bridged analogues of VEGF(81-91): potential biological tools for studying the VEGF/VEGFR-1 interaction.
García-Aranda MI, Marrero P, Gautier B, Martín-Martínez M, Inguimbert N, Vidal M, García-López MT, Jiménez MA, González-Muñiz R, Pérez de Vega MJ.
García-Aranda MI, et al.
Bioorg Med Chem. 2011 Mar 15;19(6):1978-86. doi: 10.1016/j.bmc.2011.01.056. Epub 2011 Feb 2.
Bioorg Med Chem. 2011.
PMID: 21349728
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A role for ring-closing metathesis in medicinal chemistry: mimicking secondary architectures in bioactive peptides.
Pérez de Vega MJ, García-Aranda MI, González-Muñiz R.
Pérez de Vega MJ, et al. Among authors: garcia aranda mi.
Med Res Rev. 2011 Sep;31(5):677-715. doi: 10.1002/med.20199. Epub 2010 Jan 14.
Med Res Rev. 2011.
PMID: 20077561
Review.
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