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The WNK1-ERK5 route plays a pathophysiological role in ovarian cancer and limits therapeutic efficacy of trametinib.
Sánchez-Fdez A, Matilla-Almazán S, Montero JC, Del Carmen S, Abad M, García-Alonso S, Bhattacharya S, Calar K, de la Puente P, Ocaña A, Pandiella A, Esparís-Ogando A. Sánchez-Fdez A, et al. Among authors: garcia alonso s. Clin Transl Med. 2023 Apr;13(4):e1217. doi: 10.1002/ctm2.1217. Clin Transl Med. 2023. PMID: 37029785 Free PMC article.
Multisite phosphorylation of P-Rex1 by protein kinase C.
Montero JC, Seoane S, García-Alonso S, Pandiella A. Montero JC, et al. Oncotarget. 2016 Nov 22;7(47):77937-77949. doi: 10.18632/oncotarget.12846. Oncotarget. 2016. PMID: 27788493 Free PMC article.
Resistance to Antibody-Drug Conjugates.
García-Alonso S, Ocaña A, Pandiella A. García-Alonso S, et al. Cancer Res. 2018 May 1;78(9):2159-2165. doi: 10.1158/0008-5472.CAN-17-3671. Epub 2018 Apr 13. Cancer Res. 2018. PMID: 29653942 Review.
Refining Early Antitumoral Drug Development.
Ocaña A, García-Alonso S, Amir E, Pandiella A. Ocaña A, et al. Trends Pharmacol Sci. 2018 Nov;39(11):922-925. doi: 10.1016/j.tips.2018.09.003. Epub 2018 Sep 29. Trends Pharmacol Sci. 2018. PMID: 30279003 Review.
mTOR Inhibition and T-DM1 in HER2-Positive Breast Cancer.
Casadevall D, Hernández-Prat A, García-Alonso S, Arpí-Llucià O, Menéndez S, Qin M, Guardia C, Morancho B, Sánchez-Martín FJ, Zazo S, Gavilán E, Sabbaghi MA, Eroles P, Cejalvo JM, Lluch A, Rojo F, Pandiella A, Rovira A, Albanell J. Casadevall D, et al. Among authors: garcia alonso s. Mol Cancer Res. 2022 Jul 6;20(7):1108-1121. doi: 10.1158/1541-7786.MCR-21-0545. Mol Cancer Res. 2022. PMID: 35348729
Defective Cyclin B1 Induction in Trastuzumab-emtansine (T-DM1) Acquired Resistance in HER2-positive Breast Cancer.
Sabbaghi M, Gil-Gómez G, Guardia C, Servitja S, Arpí O, García-Alonso S, Menendez S, Arumi-Uria M, Serrano L, Salido M, Muntasell A, Martínez-García M, Zazo S, Chamizo C, González-Alonso P, Madoz-Gúrpide J, Eroles P, Arribas J, Tusquets I, Lluch A, Pandiella A, Rojo F, Rovira A, Albanell J. Sabbaghi M, et al. Clin Cancer Res. 2017 Nov 15;23(22):7006-7019. doi: 10.1158/1078-0432.CCR-17-0696. Epub 2017 Aug 18. Clin Cancer Res. 2017. PMID: 28821558
34 results