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Enhanced Gene Delivery Triggered by Dual pH/Redox Responsive Host-Guest Dimerization of Cyclooligosaccharide Star Polycations.
Carbajo-Gordillo AI, López-Fernández J, Benito JM, Jiménez Blanco JL, Santana-Armas ML, Marcelo G, Di Giorgio C, Przybylski C, Ortiz Mellet C, Tros de Ilarduya C, Mendicuti F, García Fernández JM. Carbajo-Gordillo AI, et al. Among authors: garcia fernandez jm. Macromol Rapid Commun. 2022 Jun;43(11):e2200145. doi: 10.1002/marc.202200145. Epub 2022 Apr 22. Macromol Rapid Commun. 2022. PMID: 35426201
Trehalose- and glucose-derived glycoamphiphiles: small-molecule and nanoparticle Toll-like receptor 4 (TLR4) modulators.
Rodriguez Lavado J, Sestito SE, Cighetti R, Aguilar Moncayo EM, Oblak A, Lainšček D, Jiménez Blanco JL, García Fernández JM, Ortiz Mellet C, Jerala R, Calabrese V, Peri F. Rodriguez Lavado J, et al. Among authors: garcia fernandez jm. J Med Chem. 2014 Nov 13;57(21):9105-23. doi: 10.1021/jm501182w. Epub 2014 Oct 21. J Med Chem. 2014. PMID: 25268544
Inhibitor versus chaperone behaviour of d-fagomine, DAB and LAB sp(2)-iminosugar conjugates against glycosidases: A structure-activity relationship study in Gaucher fibroblasts.
Mena-Barragán T, García-Moreno MI, Nanba E, Higaki K, Concia AL, Clapés P, García Fernández JM, Ortiz Mellet C. Mena-Barragán T, et al. Among authors: garcia moreno mi, garcia fernandez jm. Eur J Med Chem. 2016 Oct 4;121:880-891. doi: 10.1016/j.ejmech.2015.08.038. Epub 2015 Aug 31. Eur J Med Chem. 2016. PMID: 26361824
pH-Responsive Pharmacological Chaperones for Rescuing Mutant Glycosidases.
Mena-Barragán T, Narita A, Matias D, Tiscornia G, Nanba E, Ohno K, Suzuki Y, Higaki K, Garcia Fernández JM, Ortiz Mellet C. Mena-Barragán T, et al. Among authors: garcia fernandez jm. Angew Chem Int Ed Engl. 2015 Sep 28;54(40):11696-700. doi: 10.1002/anie.201505147. Epub 2015 Aug 7. Angew Chem Int Ed Engl. 2015. PMID: 26386364
Fluorinated Chaperone-β-Cyclodextrin Formulations for β-Glucocerebrosidase Activity Enhancement in Neuronopathic Gaucher Disease.
García-Moreno MI, de la Mata M, Sánchez-Fernández EM, Benito JM, Díaz-Quintana A, Fustero S, Nanba E, Higaki K, Sánchez-Alcázar JA, García Fernández JM, Ortiz Mellet C. García-Moreno MI, et al. Among authors: garcia fernandez jm. J Med Chem. 2017 Mar 9;60(5):1829-1842. doi: 10.1021/acs.jmedchem.6b01550. Epub 2017 Feb 22. J Med Chem. 2017. PMID: 28171725
Molecular determinants for cyclo-oligosaccharide-based nanoparticle-mediated effective siRNA transfection.
Manzanares D, Araya-Durán I, Gallego-Yerga L, Játiva P, Márquez-Miranda V, Canan J, Jiménez Blanco JL, Mellet CO, González-Nilo FD, García Fernández JM, Ceña V. Manzanares D, et al. Among authors: garcia fernandez jm. Nanomedicine (Lond). 2017 Jul;12(13):1607-1621. doi: 10.2217/nnm-2017-0123. Epub 2017 Jun 16. Nanomedicine (Lond). 2017. PMID: 28621615
305 results