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Downregulation of PLIN2 in human dermal fibroblasts impairs mitochondrial function in an age-dependent fashion and induces cell senescence via GDF15.
Chiariello A, Rossetti L, Valente S, Pasquinelli G, Sollazzo M, Iommarini L, Porcelli AM, Tognocchi M, Conte G, Santoro A, Kwiatkowska KM, Garagnani P, Salvioli S, Conte M. Chiariello A, et al. Among authors: garagnani p. Aging Cell. 2024 Apr 22:e14111. doi: 10.1111/acel.14111. Online ahead of print. Aging Cell. 2024. PMID: 38650174 Free article.
Replicative senescence and high glucose induce the accrual of self-derived cytosolic nucleic acids in human endothelial cells.
Ramini D, Giuliani A, Kwiatkowska KM, Guescini M, Storci G, Mensà E, Recchioni R, Xumerle L, Zago E, Sabbatinelli J, Santi S, Garagnani P, Bonafè M, Olivieri F. Ramini D, et al. Among authors: garagnani p. Cell Death Discov. 2024 Apr 20;10(1):184. doi: 10.1038/s41420-024-01954-z. Cell Death Discov. 2024. PMID: 38643201 Free PMC article.
Where are we in the implementation of tissue-specific epigenetic clocks?
Sala C, Di Lena P, Fernandes Durso D, Faria do Valle I, Bacalini MG, Dall'Olio D, Franceschi C, Castellani G, Garagnani P, Nardini C. Sala C, et al. Among authors: garagnani p. Front Bioinform. 2024 Mar 4;4:1306244. doi: 10.3389/fbinf.2024.1306244. eCollection 2024. Front Bioinform. 2024. PMID: 38501111 Free PMC article.
Lipid droplets, autophagy, and ageing: A cell-specific tale.
Maestri A, Garagnani P, Pedrelli M, Hagberg CE, Parini P, Ehrenborg E. Maestri A, et al. Among authors: garagnani p. Ageing Res Rev. 2024 Feb;94:102194. doi: 10.1016/j.arr.2024.102194. Epub 2024 Jan 11. Ageing Res Rev. 2024. PMID: 38218464 Free article. Review.
Epigenetic aging differences between Wichí and Criollos from Argentina: Insights from genomic history and ecology.
Iannuzzi V, Sarno S, Sazzini M, Abondio P, Sala C, Bacalini MG, Gentilini D, Calzari L, Masciotta F, Garagnani P, Castellani G, Moretti E, Dasso MC, Sevini F, Franceschi ZA, Franceschi C, Pettener D, Luiselli D, Giuliani C. Iannuzzi V, et al. Among authors: garagnani p. Evol Med Public Health. 2023 Oct 16;11(1):397-414. doi: 10.1093/emph/eoad034. eCollection 2023. Evol Med Public Health. 2023. PMID: 37954982 Free PMC article.
Epigenomic signature of accelerated ageing in progeroid Cockayne syndrome.
Crochemore C, Chica C, Garagnani P, Lattanzi G, Horvath S, Sarasin A, Franceschi C, Bacalini MG, Ricchetti M. Crochemore C, et al. Among authors: garagnani p. Aging Cell. 2023 Oct;22(10):e13959. doi: 10.1111/acel.13959. Epub 2023 Sep 8. Aging Cell. 2023. PMID: 37688320 Free PMC article.
Centenarian clocks: epigenetic clocks for validating claims of exceptional longevity.
Dec E, Clement J, Cheng K, Church GM, Fossel MB, Rehkopf DH, Rosero-Bixby L, Kobor MS, Lin DT, Lu AT, Fei Z, Guo W, Chew YC, Yang X, Putra SED, Reiner AP, Correa A, Vilalta A, Pirazzini C, Passarino G, Monti D, Arosio B, Garagnani P, Franceschi C, Horvath S. Dec E, et al. Among authors: garagnani p. Geroscience. 2023 Jun;45(3):1817-1835. doi: 10.1007/s11357-023-00731-7. Epub 2023 Mar 25. Geroscience. 2023. PMID: 36964402 Free PMC article.
169 results