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Toxic effects of mutant huntingtin in axons are mediated by its proline-rich domain.
Brady ST, Mesnard-Hoaglin NA, Priego M, Dziechciowska J, Morris S, Kang M, Tsai MY, Purks JL, Klein A, Gaona A, Melloni A, Connors T, Hyman B, Song Y, Morfini GA. Brady ST, et al. Among authors: gaona a. Brain. 2023 Aug 26:awad280. doi: 10.1093/brain/awad280. Online ahead of print. Brain. 2023. PMID: 37633260
Changes in glial cell phenotypes precede overt neurofibrillary tangle formation, correlate with markers of cortical cell damage, and predict cognitive status of individuals at Braak III-IV stages.
Taddei RN, Sanchez-Mico MV, Bonnar O, Connors T, Gaona A, Denbow D, Frosch MP, Gómez-Isla T. Taddei RN, et al. Among authors: gaona a. Acta Neuropathol Commun. 2022 May 9;10(1):72. doi: 10.1186/s40478-022-01370-3. Acta Neuropathol Commun. 2022. PMID: 35534858 Free PMC article.
34 results