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2-Anilino-4-aryl-1,3-thiazole inhibitors of valosin-containing protein (VCP or p97).
Bursavich MG, Parker DP, Willardsen JA, Gao ZH, Davis T, Ostanin K, Robinson R, Peterson A, Cimbora DM, Zhu JF, Richards B. Bursavich MG, et al. Among authors: gao zh. Bioorg Med Chem Lett. 2010 Mar 1;20(5):1677-9. doi: 10.1016/j.bmcl.2010.01.058. Epub 2010 Jan 21. Bioorg Med Chem Lett. 2010. PMID: 20137940
Analogues of 4-[(7-Bromo-2-methyl-4-oxo-3H-quinazolin-6-yl)methylprop-2-ynylamino]-N-(3-pyridylmethyl)benzamide (CB-30865) as potent inhibitors of nicotinamide phosphoribosyltransferase (Nampt).
Lockman JW, Murphy BR, Zigar DF, Judd WR, Slattum PM, Gao ZH, Ostanin K, Green J, McKinnon R, Terry-Lorenzo RT, Fleischer TC, Boniface JJ, Shenderovich M, Willardsen JA. Lockman JW, et al. Among authors: gao zh. J Med Chem. 2010 Dec 23;53(24):8734-46. doi: 10.1021/jm101145b. Epub 2010 Nov 16. J Med Chem. 2010. PMID: 21080724
386 results