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Tumor cell-intrinsic PD-1 receptor is a tumor suppressor and mediates resistance to PD-1 blockade therapy.
Wang X, Yang X, Zhang C, Wang Y, Cheng T, Duan L, Tong Z, Tan S, Zhang H, Saw PE, Gu Y, Wang J, Zhang Y, Shang L, Liu Y, Jiang S, Yan B, Li R, Yang Y, Yu J, Chen Y, Gao GF, Ye Q, Gao S. Wang X, et al. Among authors: gao s, gao gf. Proc Natl Acad Sci U S A. 2020 Mar 24;117(12):6640-6650. doi: 10.1073/pnas.1921445117. Epub 2020 Mar 11. Proc Natl Acad Sci U S A. 2020. PMID: 32161124 Free PMC article.
Structural basis of anti-PD-L1 monoclonal antibody avelumab for tumor therapy.
Liu K, Tan S, Chai Y, Chen D, Song H, Zhang CW, Shi Y, Liu J, Tan W, Lyu J, Gao S, Yan J, Qi J, Gao GF. Liu K, et al. Among authors: gao s, gao gf. Cell Res. 2017 Jan;27(1):151-153. doi: 10.1038/cr.2016.102. Epub 2016 Aug 30. Cell Res. 2017. PMID: 27573173 Free PMC article. No abstract available.
An unexpected N-terminal loop in PD-1 dominates binding by nivolumab.
Tan S, Zhang H, Chai Y, Song H, Tong Z, Wang Q, Qi J, Wong G, Zhu X, Liu WJ, Gao S, Wang Z, Shi Y, Yang F, Gao GF, Yan J. Tan S, et al. Among authors: gao s, gao gf. Nat Commun. 2017 Feb 6;8:14369. doi: 10.1038/ncomms14369. Nat Commun. 2017. PMID: 28165004 Free PMC article.
Transcriptional Regulation of the Warburg Effect in Cancer by SIX1.
Li L, Liang Y, Kang L, Liu Y, Gao S, Chen S, Li Y, You W, Dong Q, Hong T, Yan Z, Jin S, Wang T, Zhao W, Mai H, Huang J, Han X, Ji Q, Song Q, Yang C, Zhao S, Xu X, Ye Q. Li L, et al. Among authors: gao s. Cancer Cell. 2018 Mar 12;33(3):368-385.e7. doi: 10.1016/j.ccell.2018.01.010. Epub 2018 Feb 15. Cancer Cell. 2018. PMID: 29455928 Free article.
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