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Tyrosyl-DNA-phosphodiesterases (TDP1 and TDP2).
Pommier Y, Huang SY, Gao R, Das BB, Murai J, Marchand C. Pommier Y, et al. Among authors: gao r. DNA Repair (Amst). 2014 Jul;19:114-29. doi: 10.1016/j.dnarep.2014.03.020. Epub 2014 May 22. DNA Repair (Amst). 2014. PMID: 24856239 Free PMC article. Review.
Biochemical assays for the discovery of TDP1 inhibitors.
Marchand C, Huang SY, Dexheimer TS, Lea WA, Mott BT, Chergui A, Naumova A, Stephen AG, Rosenthal AS, Rai G, Murai J, Gao R, Maloney DJ, Jadhav A, Jorgensen WL, Simeonov A, Pommier Y. Marchand C, et al. Among authors: gao r. Mol Cancer Ther. 2014 Aug;13(8):2116-26. doi: 10.1158/1535-7163.MCT-13-0952. Epub 2014 Jul 14. Mol Cancer Ther. 2014. PMID: 25024006 Free PMC article.
Structural basis for recognition of 5'-phosphotyrosine adducts by Tdp2.
Shi K, Kurahashi K, Gao R, Tsutakawa SE, Tainer JA, Pommier Y, Aihara H. Shi K, et al. Among authors: gao r. Nat Struct Mol Biol. 2012 Dec;19(12):1372-7. doi: 10.1038/nsmb.2423. Epub 2012 Oct 28. Nat Struct Mol Biol. 2012. PMID: 23104058 Free PMC article.
5,719 results