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Protein-retention expansion microscopy of cells and tissues labeled using standard fluorescent proteins and antibodies.
Tillberg PW, Chen F, Piatkevich KD, Zhao Y, Yu CC, English BP, Gao L, Martorell A, Suk HJ, Yoshida F, DeGennaro EM, Roossien DH, Gong G, Seneviratne U, Tannenbaum SR, Desimone R, Cai D, Boyden ES. Tillberg PW, et al. Among authors: gao l. Nat Biotechnol. 2016 Sep;34(9):987-92. doi: 10.1038/nbt.3625. Epub 2016 Jul 4. Nat Biotechnol. 2016. PMID: 27376584 Free PMC article.
Engineered Cpf1 variants with altered PAM specificities.
Gao L, Cox DBT, Yan WX, Manteiga JC, Schneider MW, Yamano T, Nishimasu H, Nureki O, Crosetto N, Zhang F. Gao L, et al. Nat Biotechnol. 2017 Aug;35(8):789-792. doi: 10.1038/nbt.3900. Epub 2017 Jun 5. Nat Biotechnol. 2017. PMID: 28581492 Free PMC article.
Effects of 3D culturing conditions on the transcriptomic profile of stem-cell-derived neurons.
Tekin H, Simmons S, Cummings B, Gao L, Adiconis X, Hession CC, Ghoshal A, Dionne D, Choudhury SR, Yesilyurt V, Sanjana NE, Shi X, Lu C, Heidenreich M, Pan JQ, Levin JZ, Zhang F. Tekin H, et al. Among authors: gao l. Nat Biomed Eng. 2018 Jul;2(7):540-554. doi: 10.1038/s41551-018-0219-9. Epub 2018 Apr 9. Nat Biomed Eng. 2018. PMID: 30271673 Free PMC article.
Engineering of CRISPR-Cas12b for human genome editing.
Strecker J, Jones S, Koopal B, Schmid-Burgk J, Zetsche B, Gao L, Makarova KS, Koonin EV, Zhang F. Strecker J, et al. Among authors: gao l. Nat Commun. 2019 Jan 22;10(1):212. doi: 10.1038/s41467-018-08224-4. Nat Commun. 2019. PMID: 30670702 Free PMC article.
Highly Parallel Profiling of Cas9 Variant Specificity.
Schmid-Burgk JL, Gao L, Li D, Gardner Z, Strecker J, Lash B, Zhang F. Schmid-Burgk JL, et al. Among authors: gao l. Mol Cell. 2020 May 21;78(4):794-800.e8. doi: 10.1016/j.molcel.2020.02.023. Epub 2020 Mar 17. Mol Cell. 2020. PMID: 32187529 Free PMC article.
Engineered CRISPR-Cas9 nuclease with expanded targeting space.
Nishimasu H, Shi X, Ishiguro S, Gao L, Hirano S, Okazaki S, Noda T, Abudayyeh OO, Gootenberg JS, Mori H, Oura S, Holmes B, Tanaka M, Seki M, Hirano H, Aburatani H, Ishitani R, Ikawa M, Yachie N, Zhang F, Nureki O. Nishimasu H, et al. Among authors: gao l. Science. 2018 Sep 21;361(6408):1259-1262. doi: 10.1126/science.aas9129. Epub 2018 Aug 30. Science. 2018. PMID: 30166441 Free PMC article.
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