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Phosphorylation of RXRα mediates the effect of JNK to suppress hepatic FGF21 expression and promote metabolic syndrome.
Vernia S, Lee A, Kennedy NJ, Han MS, Isasa M, Cavanagh-Kyros J, Roy A, Syed A, Chaudhry S, Edwards YJK, Gygi SP, Gao G, Davis RJ. Vernia S, et al. Among authors: gao g. Proc Natl Acad Sci U S A. 2022 Nov;119(44):e2210434119. doi: 10.1073/pnas.2210434119. Epub 2022 Oct 25. Proc Natl Acad Sci U S A. 2022. PMID: 36282921 Free PMC article.
Single-cell sequencing reveals suppressive transcriptional programs regulated by MIS/AMH in neonatal ovaries.
Meinsohn MC, Saatcioglu HD, Wei L, Li Y, Horn H, Chauvin M, Kano M, Nguyen NMP, Nagykery N, Kashiwagi A, Samore WR, Wang D, Oliva E, Gao G, Morris ME, Donahoe PK, Pépin D. Meinsohn MC, et al. Among authors: gao g. Proc Natl Acad Sci U S A. 2021 May 18;118(20):e2100920118. doi: 10.1073/pnas.2100920118. Proc Natl Acad Sci U S A. 2021. PMID: 33980714 Free PMC article.
AAV9 delivering a modified human Mullerian inhibiting substance as a gene therapy in patient-derived xenografts of ovarian cancer.
Pépin D, Sosulski A, Zhang L, Wang D, Vathipadiekal V, Hendren K, Coletti CM, Yu A, Castro CM, Birrer MJ, Gao G, Donahoe PK. Pépin D, et al. Among authors: gao g. Proc Natl Acad Sci U S A. 2015 Aug 11;112(32):E4418-27. doi: 10.1073/pnas.1510604112. Epub 2015 Jul 27. Proc Natl Acad Sci U S A. 2015. PMID: 26216943 Free PMC article.
AMH/MIS as a contraceptive that protects the ovarian reserve during chemotherapy.
Kano M, Sosulski AE, Zhang L, Saatcioglu HD, Wang D, Nagykery N, Sabatini ME, Gao G, Donahoe PK, Pépin D. Kano M, et al. Among authors: gao g. Proc Natl Acad Sci U S A. 2017 Feb 28;114(9):E1688-E1697. doi: 10.1073/pnas.1620729114. Epub 2017 Jan 30. Proc Natl Acad Sci U S A. 2017. PMID: 28137855 Free PMC article.
Divalent siRNAs are bioavailable in the lung and efficiently block SARS-CoV-2 infection.
Hariharan VN, Shin M, Chang CW, O'Reilly D, Biscans A, Yamada K, Guo Z, Somasundaran M, Tang Q, Monopoli K, Krishnamurthy PM, Devi G, McHugh N, Cooper DA, Echeverria D, Cruz J, Chan IL, Liu P, Lim SY, McConnell J, Singh SP, Hildebrand S, Sousa J, Davis SM, Kennedy Z, Ferguson C, Godinho BMDC, Thillier Y, Caiazzi J, Ly S, Muhuri M, Kelly K, Humphries F, Cousineau A, Parsi KM, Li Q, Wang Y, Maehr R, Gao G, Korkin D, McDougall WM, Finberg RW, Fitzgerald KA, Wang JP, Watts JK, Khvorova A. Hariharan VN, et al. Among authors: gao g. Proc Natl Acad Sci U S A. 2023 Mar 14;120(11):e2219523120. doi: 10.1073/pnas.2219523120. Epub 2023 Mar 9. Proc Natl Acad Sci U S A. 2023. PMID: 36893269 Free PMC article.
Gene transfer in the liver using recombinant adeno-associated virus.
Ahmed SS, Li J, Godwin J, Gao G, Zhong L. Ahmed SS, et al. Among authors: gao g. Curr Protoc Microbiol. 2013;Chapter 14:14D.6.1-14D.6.32. doi: 10.1002/9780471729259.mc14d06s29. Curr Protoc Microbiol. 2013. PMID: 23686826 Free PMC article.
6,191 results