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SAR studies of 4-acyl-1,6-dialkylpiperazin-2-one arenavirus cell entry inhibitors.
Bioorg Med Chem Lett. 2019 Nov 15;29(22):126620. doi: 10.1016/j.bmcl.2019.08.024. Epub 2019 Aug 24.
Bioorg Med Chem Lett. 2019.
PMID: 31537423
Free PMC article.
Potent inhibition of arenavirus infection by a novel fusion inhibitor.
Gowen BB, Naik S, Westover JB, Brown ER, Gantla VR, Fetsko A, Dagley AL, Blotter DJ, Anderson N, McCormack K, Henkel G.
Gowen BB, et al. Among authors: gantla vr.
Antiviral Res. 2021 Sep;193:105125. doi: 10.1016/j.antiviral.2021.105125. Epub 2021 Jun 29.
Antiviral Res. 2021.
PMID: 34197863
Free PMC article.
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Discovery of Adamantane Carboxamides as Ebola Virus Cell Entry and Glycoprotein Inhibitors.
Plewe MB, Sokolova NV, Gantla VR, Brown ER, Naik S, Fetsko A, Lorimer DD, Dranow DM, Smutney H, Bullen J, Sidhu R, Master A, Wang J, Kallel EA, Zhang L, Kalveram B, Freiberg AN, Henkel G, McCormack K.
Plewe MB, et al. Among authors: gantla vr.
ACS Med Chem Lett. 2020 May 1;11(6):1160-1167. doi: 10.1021/acsmedchemlett.0c00025. eCollection 2020 Jun 11.
ACS Med Chem Lett. 2020.
PMID: 32550996
Free PMC article.
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Discovery of a novel highly potent broad-spectrum heterocyclic chemical series of arenavirus cell entry inhibitors.
Plewe MB, Gantla VR, Sokolova NV, Shin YJ, Naik S, Brown ER, Fetsko A, Zhang L, Kalveram B, Freiberg AN, Henkel G, McCormack K.
Plewe MB, et al. Among authors: gantla vr.
Bioorg Med Chem Lett. 2021 Jun 1;41:127983. doi: 10.1016/j.bmcl.2021.127983. Epub 2021 May 5.
Bioorg Med Chem Lett. 2021.
PMID: 33965007
Free PMC article.
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Severe mammarenaviral disease in guinea pigs effectively treated by an orally bioavailable fusion inhibitor, alone or in combination with favipiravir.
Westover JB, Naik S, Bailey KW, Wandersee L, Gantla VR, Hickerson BT, McCormack K, Henkel G, Gowen BB.
Westover JB, et al. Among authors: gantla vr.
Antiviral Res. 2022 Dec;208:105444. doi: 10.1016/j.antiviral.2022.105444. Epub 2022 Oct 13.
Antiviral Res. 2022.
PMID: 36243175
Free PMC article.
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Design and synthesis of 5-aryl-pyridone-carboxamides as inhibitors of anaplastic lymphoma kinase.
Li R, Xue L, Zhu T, Jiang Q, Cui X, Yan Z, McGee D, Wang J, Gantla VR, Pickens JC, McGrath D, Chucholowski A, Morris SW, Webb TR.
Li R, et al. Among authors: gantla vr.
J Med Chem. 2006 Feb 9;49(3):1006-15. doi: 10.1021/jm050824x.
J Med Chem. 2006.
PMID: 16451066
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