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Functional characterization of 5p15.33 risk locus in uveal melanoma reveals rs452384 as a functional variant and NKX2.4 as an allele-specific interactor.
Derrien AC, Houy A, Ganier O, Dingli F, Ningarhari M, Mobuchon L, Espejo Díaz MI, Loew D, Cassoux N, Cussenot O, Cancel-Tassin G, Margueron R, Noirel J, Zucman-Rossi J, Rodrigues M, Stern MH. Derrien AC, et al. Among authors: ganier o. Am J Hum Genet. 2022 Dec 1;109(12):2196-2209. doi: 10.1016/j.ajhg.2022.11.004. Am J Hum Genet. 2022. PMID: 36459980 Free PMC article.
Cytidine analogs are synthetic lethal with base excision repair default due to MBD4 deficiency.
Chabot T, Nemati F, Herbette A, Demeyer A, Dayot S, Ganier O, Alsafadi S, Gardrat S, Mariani P, Luporsi M, Corbé M, Servois V, Cassoux N, Decaudin D, Roman SR, Del Nery E, Piperno-Neumann S, Stern MH, Rodrigues M. Chabot T, et al. Among authors: ganier o. NPJ Precis Oncol. 2022 Nov 2;6(1):81. doi: 10.1038/s41698-022-00326-z. NPJ Precis Oncol. 2022. PMID: 36323843 Free PMC article.
Splicing Patterns in SF3B1-Mutated Uveal Melanoma Generate Shared Immunogenic Tumor-Specific Neoepitopes.
Bigot J, Lalanne AI, Lucibello F, Gueguen P, Houy A, Dayot S, Ganier O, Gilet J, Tosello J, Nemati F, Pierron G, Waterfall JJ, Barnhill R, Gardrat S, Piperno-Neumann S, Popova T, Masson V, Loew D, Mariani P, Cassoux N, Amigorena S, Rodrigues M, Alsafadi S, Stern MH, Lantz O. Bigot J, et al. Among authors: ganier o. Cancer Discov. 2021 Aug;11(8):1938-1951. doi: 10.1158/2159-8290.CD-20-0555. Epub 2021 Apr 2. Cancer Discov. 2021. PMID: 33811047
Metazoan DNA replication origins.
Ganier O, Prorok P, Akerman I, Méchali M. Ganier O, et al. Curr Opin Cell Biol. 2019 Jun;58:134-141. doi: 10.1016/j.ceb.2019.03.003. Epub 2019 Jun 11. Curr Opin Cell Biol. 2019. PMID: 31200185 Review.
DNA replication origin activation in space and time.
Fragkos M, Ganier O, Coulombe P, Méchali M. Fragkos M, et al. Among authors: ganier o. Nat Rev Mol Cell Biol. 2015 Jun;16(6):360-74. doi: 10.1038/nrm4002. Nat Rev Mol Cell Biol. 2015. PMID: 25999062 Review.
16 results