Gandhirajan RK - Search Results

1

YAP-mediated mechanotransduction determines the podocyte's response to damage.

Rinschen MM, Grahammer F, Hoppe AK, Kohli P, Hagmann H, Kretz O, Bertsch S, Höhne M, Göbel H, Bartram MP, Gandhirajan RK, Krüger M, Brinkkoetter PT, Huber TB, Kann M, Wickström SA, Benzing T, Schermer B. Rinschen MM, et al. Among authors: gandhirajan rk. Sci Signal. 2017 Apr 11;10(474):eaaf8165. doi: 10.1126/scisignal.aaf8165. Sci Signal. 2017. PMID: 28400537

2

Cysteine S-Glutathionylation Promotes Stability and Activation of the Hippo Downstream Effector Transcriptional Co-activator with PDZ-binding Motif (TAZ).

Gandhirajan RK, Jain M, Walla B, Johnsen M, Bartram MP, Huynh Anh M, Rinschen MM, Benzing T, Schermer B. Gandhirajan RK, et al. J Biol Chem. 2016 May 27;291(22):11596-607. doi: 10.1074/jbc.M115.712539. Epub 2016 Apr 5. J Biol Chem. 2016. PMID: 27048650 Free PMC article.

3

Wnt/β-catenin/LEF-1 signaling in chronic lymphocytic leukemia (CLL): a target for current and potential therapeutic options.

Gandhirajan RK, Poll-Wolbeck SJ, Gehrke I, Kreuzer KA. Gandhirajan RK, et al. Curr Cancer Drug Targets. 2010 Nov;10(7):716-27. doi: 10.2174/156800910793605794. Curr Cancer Drug Targets. 2010. PMID: 20578984 Review.

4

Targeting the WNT/beta-catenin/TCF/LEF1 axis in solid and haematological cancers: Multiplicity of therapeutic options.

Gehrke I, Gandhirajan RK, Kreuzer KA. Gehrke I, et al. Among authors: gandhirajan rk. Eur J Cancer. 2009 Nov;45(16):2759-67. doi: 10.1016/j.ejca.2009.08.003. Epub 2009 Sep 2. Eur J Cancer. 2009. PMID: 19729298

5

Small molecule inhibitors of Wnt/beta-catenin/lef-1 signaling induces apoptosis in chronic lymphocytic leukemia cells in vitro and in vivo.

Gandhirajan RK, Staib PA, Minke K, Gehrke I, Plickert G, Schlösser A, Schmitt EK, Hallek M, Kreuzer KA. Gandhirajan RK, et al. Neoplasia. 2010 Apr;12(4):326-35. doi: 10.1593/neo.91972. Neoplasia. 2010. PMID: 20360943 Free PMC article.

6

Evidence for non-functional Dickkopf-1 (DKK-1) signaling in chronic lymphocytic leukemia (CLL).

Filipovich A, Gandhirajan RK, Gehrke I, Poll-Wolbeck SJ, Kreuzer KA. Filipovich A, et al. Among authors: gandhirajan rk. Eur J Haematol. 2010 Oct;85(4):309-13. doi: 10.1111/j.1600-0609.2010.01494.x. Epub 2010 Aug 30. Eur J Haematol. 2010. PMID: 20618428

7

Bone marrow stromal cell-derived vascular endothelial growth factor (VEGF) rather than chronic lymphocytic leukemia (CLL) cell-derived VEGF is essential for the apoptotic resistance of cultured CLL cells.

Gehrke I, Gandhirajan RK, Poll-Wolbeck SJ, Hallek M, Kreuzer KA. Gehrke I, et al. Among authors: gandhirajan rk. Mol Med. 2011;17(7-8):619-27. doi: 10.2119/molmed.2010.00210. Epub 2011 Apr 14. Mol Med. 2011. PMID: 21519633 Free PMC article.

8

Small molecule inhibitors of WNT signaling effectively induce apoptosis in acute myeloid leukemia cells.

Minke KS, Staib P, Puetter A, Gehrke I, Gandhirajan RK, Schlösser A, Schmitt EK, Hallek M, Kreuzer KA. Minke KS, et al. Among authors: gandhirajan rk. Eur J Haematol. 2009 Mar;82(3):165-75. doi: 10.1111/j.1600-0609.2008.01188.x. Epub 2008 Nov 20. Eur J Haematol. 2009. PMID: 19067737

9

Hyperactivation of the mammalian degenerin MDEG promotes caspase-8 activation and apoptosis.

Pan JA, Fan Y, Gandhirajan RK, Madesh M, Zong WX. Pan JA, et al. Among authors: gandhirajan rk. J Biol Chem. 2013 Feb 1;288(5):2952-63. doi: 10.1074/jbc.M112.441063. Epub 2012 Dec 13. J Biol Chem. 2013. PMID: 23239879 Free PMC article.

10

The vascular endothelial growth factor receptor tyrosine kinase inhibitors vatalanib and pazopanib potently induce apoptosis in chronic lymphocytic leukemia cells in vitro and in vivo.

Paesler J, Gehrke I, Gandhirajan RK, Filipovich A, Hertweck M, Erdfelder F, Uhrmacher S, Poll-Wolbeck SJ, Hallek M, Kreuzer KA. Paesler J, et al. Among authors: gandhirajan rk. Clin Cancer Res. 2010 Jul 1;16(13):3390-8. doi: 10.1158/1078-0432.CCR-10-0232. Epub 2010 Jun 22. Clin Cancer Res. 2010. PMID: 20570929

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