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Leucine-rich repeat kinase 2 (LRRK2): a key player in the pathogenesis of Parkinson's disease.
J Neurosci Res. 2009 May 1;87(6):1283-95. doi: 10.1002/jnr.21949.
J Neurosci Res. 2009.
PMID: 19025767
Free PMC article.
Review.
The Parkinson's disease-associated protein, leucine-rich repeat kinase 2 (LRRK2), is an authentic GTPase that stimulates kinase activity.
Guo L, Gandhi PN, Wang W, Petersen RB, Wilson-Delfosse AL, Chen SG.
Guo L, et al. Among authors: gandhi pn.
Exp Cell Res. 2007 Oct 1;313(16):3658-70. doi: 10.1016/j.yexcr.2007.07.007. Epub 2007 Jul 19.
Exp Cell Res. 2007.
PMID: 17706965
Free PMC article.
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The Roc domain of leucine-rich repeat kinase 2 is sufficient for interaction with microtubules.
Gandhi PN, Wang X, Zhu X, Chen SG, Wilson-Delfosse AL.
Gandhi PN, et al.
J Neurosci Res. 2008 Jun;86(8):1711-20. doi: 10.1002/jnr.21622.
J Neurosci Res. 2008.
PMID: 18214993
Free PMC article.
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An activating mutant of Cdc42 that fails to interact with Rho GDP-dissociation inhibitor localizes to the plasma membrane and mediates actin reorganization.
Gibson RM, Gandhi PN, Tong X, Miyoshi J, Takai Y, Konieczkowski M, Sedor JR, Wilson-Delfosse AL.
Gibson RM, et al. Among authors: gandhi pn.
Exp Cell Res. 2004 Dec 10;301(2):211-22. doi: 10.1016/j.yexcr.2004.07.033.
Exp Cell Res. 2004.
PMID: 15530857
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An activating mutant of Rac1 that fails to interact with Rho GDP-dissociation inhibitor stimulates membrane ruffling in mammalian cells.
Gandhi PN, Gibson RM, Tong X, Miyoshi J, Takai Y, Konieczkowski M, Sedor JR, Wilson-Delfosse AL.
Gandhi PN, et al.
Biochem J. 2004 Mar 1;378(Pt 2):409-19. doi: 10.1042/BJ20030979.
Biochem J. 2004.
PMID: 14629200
Free PMC article.
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