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Sensitization of DNA damage-induced apoptosis by the proteasome inhibitor PS-341 is p53 dependent and involves target proteins 14-3-3sigma and survivin.
Vaziri SA, Hill J, Chikamori K, Grabowski DR, Takigawa N, Chawla-Sarkar M, Rybicki LR, Gudkov AV, Mekhail T, Bukowski RM, Ganapathi MK, Ganapathi R. Vaziri SA, et al. Among authors: ganapathi r, ganapathi mk. Mol Cancer Ther. 2005 Dec;4(12):1880-90. doi: 10.1158/1535-7163.MCT-05-0222. Mol Cancer Ther. 2005. PMID: 16373703
Roles of the C-terminal domains of topoisomerase IIα and topoisomerase IIβ in regulation of the decatenation checkpoint.
Kozuki T, Chikamori K, Surleac MD, Micluta MA, Petrescu AJ, Norris EJ, Elson P, Hoeltge GA, Grabowski DR, Porter ACG, Ganapathi RN, Ganapathi MK. Kozuki T, et al. Among authors: ganapathi rn, ganapathi mk. Nucleic Acids Res. 2017 Jun 2;45(10):5995-6010. doi: 10.1093/nar/gkx325. Nucleic Acids Res. 2017. PMID: 28472494 Free PMC article.
Phosphorylation of serine 1106 in the catalytic domain of topoisomerase II alpha regulates enzymatic activity and drug sensitivity.
Chikamori K, Grabowski DR, Kinter M, Willard BB, Yadav S, Aebersold RH, Bukowski RM, Hickson ID, Andersen AH, Ganapathi R, Ganapathi MK. Chikamori K, et al. Among authors: ganapathi r, ganapathi mk. J Biol Chem. 2003 Apr 11;278(15):12696-702. doi: 10.1074/jbc.M300837200. Epub 2003 Feb 4. J Biol Chem. 2003. PMID: 12569090 Free article.
Apoptotic pathways of epothilone BMS 310705.
Uyar D, Takigawa N, Mekhail T, Grabowski D, Markman M, Lee F, Canetta R, Peck R, Bukowski R, Ganapathi R. Uyar D, et al. Among authors: ganapathi r. Gynecol Oncol. 2003 Oct;91(1):173-8. doi: 10.1016/s0090-8258(03)00481-5. Gynecol Oncol. 2003. PMID: 14529678
137 results