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Page 1
Biocompatible, Purified VEGF-A mRNA Improves Cardiac Function after Intracardiac Injection 1 Week Post-myocardial Infarction in Swine.
Carlsson L, Clarke JC, Yen C, Gregoire F, Albery T, Billger M, Egnell AC, Gan LM, Jennbacken K, Johansson E, Linhardt G, Martinsson S, Sadiq MW, Witman N, Wang QD, Chen CH, Wang YP, Lin S, Ticho B, Hsieh PCH, Chien KR, Fritsche-Danielson R. Carlsson L, et al. Among authors: gan lm. Mol Ther Methods Clin Dev. 2018 Apr 10;9:330-346. doi: 10.1016/j.omtm.2018.04.003. eCollection 2018 Jun 15. Mol Ther Methods Clin Dev. 2018. PMID: 30038937 Free PMC article.
Imaging of atherosclerosis in WHHL rabbits using high-resolution ultrasound.
Wetterholm R, Caidahl K, Volkmann R, Brandt-Eliasson U, Fritsche-Danielson R, Gan LM. Wetterholm R, et al. Among authors: gan lm. Ultrasound Med Biol. 2007 May;33(5):720-6. doi: 10.1016/j.ultrasmedbio.2006.11.012. Epub 2007 Mar 26. Ultrasound Med Biol. 2007. PMID: 17383806
Intradermal delivery of modified mRNA encoding VEGF-A in patients with type 2 diabetes.
Gan LM, Lagerström-Fermér M, Carlsson LG, Arfvidsson C, Egnell AC, Rudvik A, Kjaer M, Collén A, Thompson JD, Joyal J, Chialda L, Koernicke T, Fuhr R, Chien KR, Fritsche-Danielson R. Gan LM, et al. Nat Commun. 2019 Feb 20;10(1):871. doi: 10.1038/s41467-019-08852-4. Nat Commun. 2019. PMID: 30787295 Free PMC article.
Inhibiting cardiac myeloperoxidase alleviates the relaxation defect in hypertrophic cardiomyocytes.
Ramachandra CJA, Kp MMJ, Chua J, Hernandez-Resendiz S, Liehn EA, Knöll R, Gan LM, Michaëlsson E, Jonsson MKB, Ryden-Markinhuhta K, Bhat RV, Fritsche-Danielson R, Lin YH, Sadayappan S, Tang HC, Wong P, Shim W, Hausenloy DJ. Ramachandra CJA, et al. Among authors: gan lm. Cardiovasc Res. 2022 Jan 29;118(2):517-530. doi: 10.1093/cvr/cvab077. Cardiovasc Res. 2022. PMID: 33705529 Free PMC article.
Citrate-Saline-Formulated mRNA Delivery into the Heart Muscle with an Electromechanical Mapping and Injection Catheter Does Not Lead to Therapeutic Effects in a Porcine Chronic Myocardial Ischemia Model.
Järveläinen N, Halonen P, Nurro J, Hätinen OP, Korpela H, Mäkinen P, Gan LM, Fritsche-Danielson R, Ylä-Herttuala S. Järveläinen N, et al. Among authors: gan lm. Hum Gene Ther. 2021 Oct;32(19-20):1295-1307. doi: 10.1089/hum.2021.149. Hum Gene Ther. 2021. PMID: 34494459
VEGFA mRNA for regenerative treatment of heart failure.
Collén A, Bergenhem N, Carlsson L, Chien KR, Hoge S, Gan LM, Fritsche-Danielson R. Collén A, et al. Among authors: gan lm. Nat Rev Drug Discov. 2022 Jan;21(1):79-80. doi: 10.1038/s41573-021-00355-6. Nat Rev Drug Discov. 2022. PMID: 34873303 Free PMC article. No abstract available.
Direct intramyocardial injection of VEGF mRNA in patients undergoing coronary artery bypass grafting.
Anttila V, Saraste A, Knuuti J, Hedman M, Jaakkola P, Laugwitz KL, Krane M, Jeppsson A, Sillanmäki S, Rosenmeier J, Zingmark P, Rudvik A, Garkaviy P, Watson C, Pangalos MN, Chien KR, Fritsche-Danielson R, Collén A, Gan LM. Anttila V, et al. Among authors: gan lm. Mol Ther. 2023 Mar 1;31(3):866-874. doi: 10.1016/j.ymthe.2022.11.017. Epub 2022 Dec 17. Mol Ther. 2023. PMID: 36528793 Free PMC article. Clinical Trial.
156 results