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The pregnane X receptor drives sexually dimorphic hepatic changes in lipid and xenobiotic metabolism in response to gut microbiota in mice.
Barretto SA, Lasserre F, Huillet M, Régnier M, Polizzi A, Lippi Y, Fougerat A, Person E, Bruel S, Bétoulières C, Naylies C, Lukowicz C, Smati S, Guzylack L, Olier M, Théodorou V, Mselli-Lakhal L, Zalko D, Wahli W, Loiseau N, Gamet-Payrastre L, Guillou H, Ellero-Simatos S. Barretto SA, et al. Among authors: gamet payrastre l. Microbiome. 2021 Apr 20;9(1):93. doi: 10.1186/s40168-021-01050-9. Microbiome. 2021. PMID: 33879258 Free PMC article.
Activation of the Constitutive Androstane Receptor induces hepatic lipogenesis and regulates Pnpla3 gene expression in a LXR-independent way.
Marmugi A, Lukowicz C, Lasserre F, Montagner A, Polizzi A, Ducheix S, Goron A, Gamet-Payrastre L, Gerbal-Chaloin S, Pascussi JM, Moldes M, Pineau T, Guillou H, Mselli-Lakhal L. Marmugi A, et al. Toxicol Appl Pharmacol. 2016 Jul 15;303:90-100. doi: 10.1016/j.taap.2016.05.006. Epub 2016 May 11. Toxicol Appl Pharmacol. 2016. PMID: 27180240
Metabolic Effects of a Chronic Dietary Exposure to a Low-Dose Pesticide Cocktail in Mice: Sexual Dimorphism and Role of the Constitutive Androstane Receptor.
Lukowicz C, Ellero-Simatos S, Régnier M, Polizzi A, Lasserre F, Montagner A, Lippi Y, Jamin EL, Martin JF, Naylies C, Canlet C, Debrauwer L, Bertrand-Michel J, Al Saati T, Théodorou V, Loiseau N, Mselli-Lakhal L, Guillou H, Gamet-Payrastre L. Lukowicz C, et al. Environ Health Perspect. 2018 Jun 25;126(6):067007. doi: 10.1289/EHP2877. eCollection 2018 Jun. Environ Health Perspect. 2018. PMID: 29950287 Free PMC article.
Gene Expression Profiling Reveals that PXR Activation Inhibits Hepatic PPARα Activity and Decreases FGF21 Secretion in Male C57Bl6/J Mice.
Barretto SA, Lasserre F, Fougerat A, Smith L, Fougeray T, Lukowicz C, Polizzi A, Smati S, Régnier M, Naylies C, Bétoulières C, Lippi Y, Guillou H, Loiseau N, Gamet-Payrastre L, Mselli-Lakhal L, Ellero-Simatos S. Barretto SA, et al. Int J Mol Sci. 2019 Aug 1;20(15):3767. doi: 10.3390/ijms20153767. Int J Mol Sci. 2019. PMID: 31374856 Free PMC article.
Dimorphic metabolic and endocrine disorders in mice lacking the constitutive androstane receptor.
Lukowicz C, Ellero-Simatos S, Régnier M, Oliviero F, Lasserre F, Polizzi A, Montagner A, Smati S, Boudou F, Lenfant F, Guzylack-Pirou L, Menard S, Barretto S, Fougerat A, Lippi Y, Naylies C, Bertrand-Michel J, Belgnaoui AA, Theodorou V, Marchi N, Gourdy P, Gamet-Payrastre L, Loiseau N, Guillou H, Mselli-Lakhal L. Lukowicz C, et al. Sci Rep. 2019 Dec 27;9(1):20169. doi: 10.1038/s41598-019-56570-0. Sci Rep. 2019. PMID: 31882815 Free PMC article.
Author Correction: Dimorphic metabolic and endocrine disorders in mice lacking the constitutive androstane receptor.
Lukowicz C, Ellero-Simatos S, Régnier M, Oliviero F, Lasserre F, Polizzi A, Montagner A, Smati S, Boudou F, Lenfant F, Guzylack-Pirou L, Menard S, Barretto S, Fougerat A, Lippi Y, Naylies C, Bertrand-Michel J, Belgnaoui AA, Theodorou V, Marchi N, Gourdy P, Gamet-Payrastre L, Loiseau N, Guillou H, Mselli-Lakhal L. Lukowicz C, et al. Sci Rep. 2020 Mar 3;10(1):4256. doi: 10.1038/s41598-020-61226-5. Sci Rep. 2020. PMID: 32123278 Free PMC article.
Life-long Dietary Pesticide Cocktail Induces Astrogliosis Along with Behavioral Adaptations and Activates p450 Metabolic Pathways.
Klement W, Oliviero F, Gangarossa G, Zub E, De Bock F, Forner-Piquer I, Blaquiere M, Lasserre F, Pascussi JM, Maurice T, Audinat E, Ellero-Simatos S, Gamet-Payrastre L, Mselli-Lakhal L, Marchi N. Klement W, et al. Neuroscience. 2020 Oct 15;446:225-237. doi: 10.1016/j.neuroscience.2020.07.039. Epub 2020 Jul 28. Neuroscience. 2020. PMID: 32736067
Perinatal exposure to a dietary pesticide cocktail does not increase susceptibility to high-fat diet-induced metabolic perturbations at adulthood but modifies urinary and fecal metabolic fingerprints in C57Bl6/J mice.
Smith L, Klément W, Dopavogui L, de Bock F, Lasserre F, Barretto S, Lukowicz C, Fougerat A, Polizzi A, Schaal B, Patris B, Denis C, Feuillet G, Canlet C, Jamin EL, Debrauwer L, Mselli-Lakhal L, Loiseau N, Guillou H, Marchi N, Ellero-Simatos S, Gamet-Payrastre L. Smith L, et al. Environ Int. 2020 Nov;144:106010. doi: 10.1016/j.envint.2020.106010. Epub 2020 Jul 31. Environ Int. 2020. PMID: 32745781 Free article.
Differential impact of dose-range glyphosate on locomotor behavior, neuronal activity, glio-cerebrovascular structures, and transcript regulations in zebrafish larvae.
Forner-Piquer I, Faucherre A, Byram J, Blaquiere M, de Bock F, Gamet-Payrastre L, Ellero-Simatos S, Audinat E, Jopling C, Marchi N. Forner-Piquer I, et al. Chemosphere. 2021 Mar;267:128986. doi: 10.1016/j.chemosphere.2020.128986. Epub 2020 Dec 4. Chemosphere. 2021. PMID: 33359984 Free article.
45 results