Gamble AB - Search Results

1

Multiple binding modes of isothiocyanates that inhibit macrophage migration inhibitory factor.

Spencer ES, Dale EJ, Gommans AL, Rutledge MT, Vo CT, Nakatani Y, Gamble AB, Smith RA, Wilbanks SM, Hampton MB, Tyndall JD. Spencer ES, et al. Among authors: gamble ab. Eur J Med Chem. 2015 Mar 26;93:501-10. doi: 10.1016/j.ejmech.2015.02.012. Epub 2015 Feb 24. Eur J Med Chem. 2015. PMID: 25743213

2

Proteases and protease inhibitors in infectious diseases.

Agbowuro AA, Huston WM, Gamble AB, Tyndall JDA. Agbowuro AA, et al. Among authors: gamble ab. Med Res Rev. 2018 Jul;38(4):1295-1331. doi: 10.1002/med.21475. Epub 2017 Nov 17. Med Res Rev. 2018. PMID: 29149530 Review.

3

Optimization of peptide-based inhibitors targeting the HtrA serine protease in Chlamydia: Design, synthesis and biological evaluation of pyridone-based and N-Capping group-modified analogues.

Hwang J, Strange N, Phillips MJA, Krause AL, Heywood A, Gamble AB, Huston WM, Tyndall JDA. Hwang J, et al. Among authors: gamble ab. Eur J Med Chem. 2021 Nov 15;224:113692. doi: 10.1016/j.ejmech.2021.113692. Epub 2021 Jul 7. Eur J Med Chem. 2021. PMID: 34265463

4

Design, synthesis and biological evaluation of P2-modified proline analogues targeting the HtrA serine protease in Chlamydia.

Hwang J, Strange N, Mazraani R, Phillips MJ, Gamble AB, Huston WM, Tyndall JDA. Hwang J, et al. Among authors: gamble ab. Eur J Med Chem. 2022 Feb 15;230:114064. doi: 10.1016/j.ejmech.2021.114064. Epub 2021 Dec 31. Eur J Med Chem. 2022. PMID: 35007862

5

Structure-activity analysis of peptidic Chlamydia HtrA inhibitors.

Agbowuro AA, Hwang J, Peel E, Mazraani R, Springwald A, Marsh JW, McCaughey L, Gamble AB, Huston WM, Tyndall JDA. Agbowuro AA, et al. Among authors: gamble ab. Bioorg Med Chem. 2019 Sep 15;27(18):4185-4199. doi: 10.1016/j.bmc.2019.07.049. Epub 2019 Jul 30. Bioorg Med Chem. 2019. PMID: 31395511

6

Stability, Kinetic, and Mechanistic Investigation of 1,8-Self-Immolative Cinnamyl Ether Spacers for Controlled Release of Phenols and Generation of Resonance and Inductively Stabilized Methides.

Matikonda SS, Fairhall JM, Tyndall JD, Hook S, Gamble AB. Matikonda SS, et al. Among authors: gamble ab. Org Lett. 2017 Feb 3;19(3):528-531. doi: 10.1021/acs.orglett.6b03695. Epub 2017 Jan 12. Org Lett. 2017. PMID: 28080067

7

Improving Antibacterial Activity of a HtrA Protease Inhibitor JO146 against Helicobacter pylori: A Novel Approach Using Microfluidics-Engineered PLGA Nanoparticles.

Hwang J, Mros S, Gamble AB, Tyndall JDA, McDowell A. Hwang J, et al. Among authors: gamble ab. Pharmaceutics. 2022 Feb 1;14(2):348. doi: 10.3390/pharmaceutics14020348. Pharmaceutics. 2022. PMID: 35214080 Free PMC article.

8

Synthesis and Biological Evaluation of Aurachin D Analogues as Inhibitors of Mycobacterium tuberculosis Cytochrome bd Oxidase.

Lawer A, Tyler C, Hards K, Keighley LM, Cheung CY, Kierek F, Su S, Matikonda SS, McInnes T, Tyndall JDA, Krause KL, Cook GM, Gamble AB. Lawer A, et al. Among authors: gamble ab. ACS Med Chem Lett. 2022 Sep 26;13(10):1663-1669. doi: 10.1021/acsmedchemlett.2c00401. eCollection 2022 Oct 13. ACS Med Chem Lett. 2022. PMID: 36262396 Free PMC article.

9

EGFR-targeted prodrug activation using bioorthogonal alkene-azide click-and-release chemistry.

Fairhall JM, Camilli JC, Gibson BH, Hook S, Gamble AB. Fairhall JM, et al. Among authors: gamble ab. Bioorg Med Chem. 2021 Sep 15;46:116361. doi: 10.1016/j.bmc.2021.116361. Epub 2021 Aug 8. Bioorg Med Chem. 2021. PMID: 34411983

10

Prohormone-substrate peptide sequence recognition by peptidylglycine α-amidating monooxygenase and its reflection in increased glycolate inhibitor potency.

Morris KM, Cao F, Onagi H, Altamore TM, Gamble AB, Easton CJ. Morris KM, et al. Among authors: gamble ab. Bioorg Med Chem Lett. 2012 Dec 1;22(23):7015-8. doi: 10.1016/j.bmcl.2012.10.004. Epub 2012 Oct 11. Bioorg Med Chem Lett. 2012. PMID: 23084901

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

32 results

Search Page