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Dynamic RNA acetylation revealed by quantitative cross-evolutionary mapping.
Sas-Chen A, Thomas JM, Matzov D, Taoka M, Nance KD, Nir R, Bryson KM, Shachar R, Liman GLS, Burkhart BW, Gamage ST, Nobe Y, Briney CA, Levy MJ, Fuchs RT, Robb GB, Hartmann J, Sharma S, Lin Q, Florens L, Washburn MP, Isobe T, Santangelo TJ, Shalev-Benami M, Meier JL, Schwartz S. Sas-Chen A, et al. Among authors: gamage st. Nature. 2020 Jul;583(7817):638-643. doi: 10.1038/s41586-020-2418-2. Epub 2020 Jun 17. Nature. 2020. PMID: 32555463 Free PMC article.
Remodelin Is a Cryptic Assay Interference Chemotype That Does Not Inhibit NAT10-Dependent Cytidine Acetylation.
Shrimp JH, Jing Y, Gamage ST, Nelson KM, Han J, Bryson KM, Montgomery DC, Thomas JM, Nance KD, Sharma S, Fox SD, Andressen T, Sinclair WR, Wu H, Allali-Hassani A, Senisterra G, Vedadi M, Lafontaine D, Dahlin JL, Marmorstein R, Walters MA, Meier JL. Shrimp JH, et al. Among authors: gamage st. ACS Med Chem Lett. 2020 Jul 27;12(6):887-892. doi: 10.1021/acsmedchemlett.0c00193. eCollection 2021 Jun 10. ACS Med Chem Lett. 2020. PMID: 34141066 Free PMC article.
Cytidine acetylation yields a hypoinflammatory synthetic messenger RNA.
Nance KD, Gamage ST, Alam MM, Yang A, Levy MJ, Link CN, Florens L, Washburn MP, Gu S, Oppenheim JJ, Meier JL. Nance KD, et al. Among authors: gamage st. Cell Chem Biol. 2022 Feb 17;29(2):312-320.e7. doi: 10.1016/j.chembiol.2021.07.003. Epub 2021 Aug 25. Cell Chem Biol. 2022. PMID: 35180432 Free PMC article.
Molecular Basis for RNA Cytidine Acetylation by NAT10.
Zhou M, Gamage ST, Tran KA, Bartee D, Wei X, Yin B, Berger S, Meier JL, Marmorstein R. Zhou M, et al. Among authors: gamage st. bioRxiv [Preprint]. 2024 Mar 27:2024.03.27.587050. doi: 10.1101/2024.03.27.587050. bioRxiv. 2024. PMID: 38585770 Free PMC article. Preprint.
Rewiring of RNA methylation by the oncometabolite fumarate in renal cell carcinoma.
Fitzsimmons CM, Mandler MD, Lunger JC, Chan D, Maligireddy SS, Schmiechen AC, Gamage ST, Link C, Jenkins LM, Chan K, Andresson T, Crooks DR, Meier JL, Linehan WM, Batista PJ. Fitzsimmons CM, et al. Among authors: gamage st. NAR Cancer. 2024 Feb 7;6(1):zcae004. doi: 10.1093/narcan/zcae004. eCollection 2024 Mar. NAR Cancer. 2024. PMID: 38328795 Free PMC article.
Loss of NAT10 disrupts enhancer organization via p300 mislocalization and suppresses transcription of genes necessary for metastasis progression.
Amin R, Ha NH, Qiu T, Holewinski R, Lam KC, Lopès A, Liu H, Tran AD, Lee MP, Gamage ST, Andresson T, Goldszmid RS, Meier JL, Hunter KW. Amin R, et al. Among authors: gamage st. bioRxiv [Preprint]. 2024 Jan 29:2024.01.24.577116. doi: 10.1101/2024.01.24.577116. bioRxiv. 2024. PMID: 38410432 Free PMC article. Preprint.