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A concept of dual-responsive prodrugs based on oligomerization-controlled reactivity of ester groups: an improvement of cancer cells versus neutrophils selectivity of camptothecin.
Klemt I, Reshetnikov V, Dutta S, Bila G, Bilyy R, Cuartero IC, Hidalgo A, Wünsche A, Böhm M, Wondrak M, Kunz-Schughart LA, Tietze R, Beierlein F, Imhof P, Gensberger-Reigl S, Pischetsrieder M, Körber M, Jost T, Mokhir A. Klemt I, et al. Among authors: bila g. RSC Med Chem. 2024 Jan 31;15(4):1189-1197. doi: 10.1039/d3md00609c. eCollection 2024 Apr 24. RSC Med Chem. 2024. PMID: 38665843 Free PMC article.
Neutrophil Activity and Extracellular Matrix Degradation: Drivers of Lung Tissue Destruction in Fatal COVID-19 Cases and Implications for Long COVID.
Narasaraju T, Neeli I, Criswell SL, Krishnappa A, Meng W, Silva V, Bila G, Vovk V, Serhiy Z, Bowlin GL, Meyer N, Luning Prak ET, Radic M, Bilyy R. Narasaraju T, et al. Among authors: bila g. Biomolecules. 2024 Feb 17;14(2):236. doi: 10.3390/biom14020236. Biomolecules. 2024. PMID: 38397474 Free PMC article.
3D-Shaped Binders of Unfolded Proteins Inducing Cancer Cell-Specific Endoplasmic Reticulum Stress In Vitro and In Vivo.
Klemt I, Varzatskii O, Selin R, Vakarov S, Kovalska V, Bila G, Bilyy R, Voloshin Y, Cuartero IC, Hidalgo A, Frey B, Becker I, Friedrich B, Tietze R, Friedrich RP, Alexiou C, Ursu EL, Rotaru A, Solymosi I, Pérez-Ojeda ME, Mokhir A. Klemt I, et al. Among authors: bila g. J Am Chem Soc. 2023 Oct 11;145(40):22252-22264. doi: 10.1021/jacs.3c08827. Epub 2023 Sep 29. J Am Chem Soc. 2023. PMID: 37773090
Suppression of neutrophils by sodium exacerbates oxidative stress and arthritis.
Zlatar L, Mahajan A, Muñoz-Becerra M, Weidner D, Bila G, Bilyy R, Titze J, Hoffmann MH, Schett G, Herrmann M, Steffen U, Muñoz LE, Knopf J. Zlatar L, et al. Among authors: bila g. Front Immunol. 2023 Aug 2;14:1174537. doi: 10.3389/fimmu.2023.1174537. eCollection 2023. Front Immunol. 2023. PMID: 37600805 Free PMC article.
13 results