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Mediation of antitumor activity by AZD4820 oncolytic vaccinia virus encoding IL-12.
Kurokawa C, Agrawal S, Mitra A, Galvani E, Burke S, Varshine A, Rothstein R, Schifferli K, Monks NR, Foloppe J, Silvestre N, Quemeneur E, Demeusoit C, Kleinpeter P, Sapra P, Barrett C, Hammond SA, Kelly EJ, Laliberte J, Durham NM, Oberst M, Broggi MAS. Kurokawa C, et al. Among authors: galvani e. Mol Ther Oncol. 2024 Jan 10;32(1):200758. doi: 10.1016/j.omton.2023.200758. eCollection 2024 Mar 21. Mol Ther Oncol. 2024. PMID: 38596304 Free PMC article.
Efficacy and pharmacodynamic effect of anti-CD73 and anti-PD-L1 monoclonal antibodies in combination with cytotoxic therapy: observations from mouse tumor models.
Kaistha BP, Kar G, Dannhorn A, Watkins A, Opoku-Ansah G, Ilieva K, Mullins S, Anderton J, Galvani E, Garcon F, Lapointe JM, Brown L, Hair J, Slidel T, Luheshi N, Ryan K, Hardaker E, Dovedi S, Kumar R, Wilkinson RW, Hammond SA, Eyles J. Kaistha BP, et al. Among authors: galvani e. Cancer Biol Ther. 2024 Dec 31;25(1):2296048. doi: 10.1080/15384047.2023.2296048. Epub 2024 Jan 11. Cancer Biol Ther. 2024. PMID: 38206570 Free PMC article.
Tumour infiltrating B cells discriminate checkpoint blockade-induced responses.
Valpione S, Campana LG, Weightman J, Salih Z, Galvani E, Mundra PA, De Rosa F, Gupta A, Serra-Bellver P, Lorigan P, Germetaki T, Dynowski M, Kitcatt S, Sahoo S, Lee D, Dhomen N, Lord G, Marais R. Valpione S, et al. Among authors: galvani e. Eur J Cancer. 2022 Dec;177:164-174. doi: 10.1016/j.ejca.2022.09.022. Epub 2022 Oct 5. Eur J Cancer. 2022. PMID: 36347135 Free article.
T cell immune awakening in response to immunotherapy is age-dependent.
Salih Z, Banyard A, Tweedy J, Galvani E, Middlehurst P, Mills S, Weightman J, Gupta A, Lorigan PC, Zhou C, Dhomen N, Valpione S, Marais R. Salih Z, et al. Among authors: galvani e. Eur J Cancer. 2022 Feb;162:11-21. doi: 10.1016/j.ejca.2021.11.015. Epub 2021 Dec 21. Eur J Cancer. 2022. PMID: 34952479 Free PMC article.
Novel non-terminal tumor sampling procedure using fine needle aspiration supports immuno-oncology biomarker discovery in preclinical mouse models.
Sitnikova SI, Munnings-Tomes S, Galvani E, Kentner S, Mulgrew K, Rands C, España Agustí J, Zhang T, Ilieva KM, Rosignoli G, Ghadially H, Robinson MJ, Slidel T, Wilkinson RW, Dovedi SJ. Sitnikova SI, et al. Among authors: galvani e. J Immunother Cancer. 2021 Jun;9(6):e002894. doi: 10.1136/jitc-2021-002894. J Immunother Cancer. 2021. PMID: 34145033 Free PMC article.
Brain microenvironment-driven resistance to immune and targeted therapies in acral melanoma.
Lee RJ, Khandelwal G, Baenke F, Cannistraci A, Macleod K, Mundra P, Ashton G, Mandal A, Viros A, Gremel G, Galvani E, Smith M, Carragher N, Dhomen N, Miller C, Lorigan P, Marais R. Lee RJ, et al. Among authors: galvani e. ESMO Open. 2020 Aug;5(4):e000707. doi: 10.1136/esmoopen-2020-000707. ESMO Open. 2020. PMID: 32817058 Free PMC article.
Immune-awakening revealed by peripheral T cell dynamics after one cycle of immunotherapy.
Valpione S, Galvani E, Tweedy J, Mundra PA, Banyard A, Middlehurst P, Barry J, Mills S, Salih Z, Weightman J, Gupta A, Gremel G, Baenke F, Dhomen N, Lorigan PC, Marais R. Valpione S, et al. Among authors: galvani e. Nat Cancer. 2020 Feb;1(2):210-221. doi: 10.1038/s43018-019-0022-x. Epub 2020 Feb 10. Nat Cancer. 2020. PMID: 32110781 Free PMC article.
Stroma remodeling and reduced cell division define durable response to PD-1 blockade in melanoma.
Galvani E, Mundra PA, Valpione S, Garcia-Martinez P, Smith M, Greenall J, Thakur R, Helmink B, Andrews MC, Boon L, Chester C, Gremel G, Hogan K, Mandal A, Zeng K, Banyard A, Ashton G, Cook M, Lorigan P, Wargo JA, Dhomen N, Marais R. Galvani E, et al. Nat Commun. 2020 Feb 12;11(1):853. doi: 10.1038/s41467-020-14632-2. Nat Commun. 2020. PMID: 32051401 Free PMC article.
56 results