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Inhibition of ADAM17 impairs endothelial cell necroptosis and blocks metastasis.
Bolik J, Krause F, Stevanovic M, Gandraß M, Thomsen I, Schacht SS, Rieser E, Müller M, Schumacher N, Fritsch J, Wichert R, Galun E, Bergmann J, Röder C, Schafmayer C, Egberts JH, Becker-Pauly C, Saftig P, Lucius R, Schneider-Brachert W, Barikbin R, Adam D, Voss M, Hitzl W, Krüger A, Strilic B, Sagi I, Walczak H, Rose-John S, Schmidt-Arras D. Bolik J, et al. Among authors: galun e. J Exp Med. 2022 Jan 3;219(1):e20201039. doi: 10.1084/jem.20201039. Epub 2021 Dec 17. J Exp Med. 2022. PMID: 34919140 Free PMC article.
The regenerative activity of interleukin-6.
Galun E, Rose-John S. Galun E, et al. Methods Mol Biol. 2013;982:59-77. doi: 10.1007/978-1-62703-308-4_4. Methods Mol Biol. 2013. PMID: 23456862
The two facets of gp130 signalling in liver tumorigenesis.
Schmidt-Arras D, Galun E, Rose-John S. Schmidt-Arras D, et al. Among authors: galun e. Semin Immunopathol. 2021 Aug;43(4):609-624. doi: 10.1007/s00281-021-00861-0. Epub 2021 May 28. Semin Immunopathol. 2021. PMID: 34047814 Free PMC article. Review.
In vivo evidence suggesting reciprocal renal hypoxia-inducible factor-1 upregulation and signal transducer and activator of transcription 3 activation in response to hypoxic and non-hypoxic stimuli.
Nechemia-Arbely Y, Khamaisi M, Rosenberger C, Koesters R, Shina A, Geva C, Shriki A, Klaus S, Rosen S, Rose-John S, Galun E, Axelrod JH, Heyman SN. Nechemia-Arbely Y, et al. Among authors: galun e. Clin Exp Pharmacol Physiol. 2013 Apr;40(4):262-72. doi: 10.1111/1440-1681.12064. Clin Exp Pharmacol Physiol. 2013. PMID: 23384058
IL-6/IL-6R axis plays a critical role in acute kidney injury.
Nechemia-Arbely Y, Barkan D, Pizov G, Shriki A, Rose-John S, Galun E, Axelrod JH. Nechemia-Arbely Y, et al. Among authors: galun e. J Am Soc Nephrol. 2008 Jun;19(6):1106-15. doi: 10.1681/ASN.2007070744. Epub 2008 Mar 12. J Am Soc Nephrol. 2008. PMID: 18337485 Free PMC article.
Single-cell transcriptomics reveals a senescence-associated IL-6/CCR6 axis driving radiodermatitis.
Paldor M, Levkovitch-Siany O, Eidelshtein D, Adar R, Enk CD, Marmary Y, Elgavish S, Nevo Y, Benyamini H, Plaschkes I, Klein S, Mali A, Rose-John S, Peled A, Galun E, Axelrod JH. Paldor M, et al. Among authors: galun e. EMBO Mol Med. 2022 Aug 8;14(8):e15653. doi: 10.15252/emmm.202115653. Epub 2022 Jul 4. EMBO Mol Med. 2022. PMID: 35785521 Free PMC article.
Interleukin 6-dependent genomic instability heralds accelerated carcinogenesis following liver regeneration on a background of chronic hepatitis.
Lanton T, Shriki A, Nechemia-Arbely Y, Abramovitch R, Levkovitch O, Adar R, Rosenberg N, Paldor M, Goldenberg D, Sonnenblick A, Peled A, Rose-John S, Galun E, Axelrod JH. Lanton T, et al. Among authors: galun e. Hepatology. 2017 May;65(5):1600-1611. doi: 10.1002/hep.29004. Epub 2017 Mar 23. Hepatology. 2017. PMID: 28027584
321 results