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The selective cytotoxic activity in breast cancer cells by an anthranilic alcohol-derived acyclic 5-fluorouracil O,N-acetal is mediated by endoplasmic reticulum stress-induced apoptosis.
Caba O, Rodríguez-Serrano F, Díaz-Gavilán M, Conejo-García A, Ortiz R, Martínez-Amat A, Alvarez P, Gallo MA, Campos JM, Marchal JA, Aránega A. Caba O, et al. Among authors: gallo ma. Eur J Med Chem. 2012 Apr;50:376-82. doi: 10.1016/j.ejmech.2012.02.017. Epub 2012 Feb 17. Eur J Med Chem. 2012. PMID: 22373735
Actual targets in cytodifferentiation cancer therapy.
Gómez-Vidal JA, Campos J, Marchal JA, Boulaiz H, Gallo MA, Carrillo E, Espinosa A, Aránega A. Gómez-Vidal JA, et al. Among authors: gallo ma. Curr Top Med Chem. 2004;4(2):175-202. doi: 10.2174/1568026043451492. Curr Top Med Chem. 2004. PMID: 14754453 Review.
A synthetic uracil derivative with antitumor activity through decreasing cyclin D1 and Cdk1, and increasing p21 and p27 in MCF-7 cells.
Marchal JA, Núñez MC, Suárez I, Díaz-Gavilán M, Gómez-Vidal JA, Boulaiz H, Rodríguez-Serrano F, Gallo MA, Espinosa A, Aránega A, Campos JM. Marchal JA, et al. Among authors: gallo ma. Breast Cancer Res Treat. 2007 Nov;105(3):237-46. doi: 10.1007/s10549-006-9450-2. Epub 2006 Nov 24. Breast Cancer Res Treat. 2007. PMID: 17124554
Regiospecific microwave-assisted synthesis and cytotoxic activity against human breast cancer cells of (RS)-6-substituted-7- or 9-(2,3-dihydro-5H-1,4-benzodioxepin-3-yl)-7H- or -9H-purines.
Conejo-García A, Núñez MC, Marchal JA, Rodríguez-Serrano F, Aránega A, Gallo MA, Espinosa A, Campos JM. Conejo-García A, et al. Among authors: gallo ma. Eur J Med Chem. 2008 Aug;43(8):1742-8. doi: 10.1016/j.ejmech.2007.10.025. Epub 2007 Oct 25. Eur J Med Chem. 2008. PMID: 18069093
196 results