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Vaccine composition formulated with a novel TLR7-dependent adjuvant induces high and broad protection against Staphylococcus aureus.
Bagnoli F, Fontana MR, Soldaini E, Mishra RP, Fiaschi L, Cartocci E, Nardi-Dei V, Ruggiero P, Nosari S, De Falco MG, Lofano G, Marchi S, Galletti B, Mariotti P, Bacconi M, Torre A, Maccari S, Scarselli M, Rinaudo CD, Inoshima N, Savino S, Mori E, Rossi-Paccani S, Baudner B, Pallaoro M, Swennen E, Petracca R, Brettoni C, Liberatori S, Norais N, Monaci E, Bubeck Wardenburg J, Schneewind O, O'Hagan DT, Valiante NM, Bensi G, Bertholet S, De Gregorio E, Rappuoli R, Grandi G. Bagnoli F, et al. Among authors: galletti b. Proc Natl Acad Sci U S A. 2015 Mar 24;112(12):3680-5. doi: 10.1073/pnas.1424924112. Epub 2015 Mar 9. Proc Natl Acad Sci U S A. 2015. PMID: 25775551 Free PMC article.
Auto-Assembling Detoxified Staphylococcus aureus Alpha-Hemolysin Mimicking the Wild-Type Cytolytic Toxin.
Fiaschi L, Di Palo B, Scarselli M, Pozzi C, Tomaszewski K, Galletti B, Nardi-Dei V, Arcidiacono L, Mishra RP, Mori E, Pallaoro M, Falugi F, Torre A, Fontana MR, Soriani M, Bubeck Wardenburg J, Grandi G, Rappuoli R, Ferlenghi I, Bagnoli F. Fiaschi L, et al. Among authors: galletti b. Clin Vaccine Immunol. 2016 Jun 6;23(6):442-50. doi: 10.1128/CVI.00091-16. Print 2016 Jun. Clin Vaccine Immunol. 2016. PMID: 27030589 Free PMC article.
RrgB321, a fusion protein of the three variants of the pneumococcal pilus backbone RrgB, is protective in vivo and elicits opsonic antibodies.
Harfouche C, Filippini S, Gianfaldoni C, Ruggiero P, Moschioni M, Maccari S, Pancotto L, Arcidiacono L, Galletti B, Censini S, Mori E, Giuliani M, Facciotti C, Cartocci E, Savino S, Doro F, Pallaoro M, Nocadello S, Mancuso G, Haston M, Goldblatt D, Barocchi MA, Pizza M, Rappuoli R, Masignani V. Harfouche C, et al. Among authors: galletti b. Infect Immun. 2012 Jan;80(1):451-60. doi: 10.1128/IAI.05780-11. Epub 2011 Nov 14. Infect Immun. 2012. PMID: 22083702 Free PMC article.
Protective effect of Group B Streptococcus type-III polysaccharide conjugates against maternal colonization, ascending infection and neonatal transmission in rodent models.
Chiarot E, Spagnuolo A, Maccari S, Naimo E, Acquaviva A, Cecchi R, Galletti B, Fabbrini M, Mori E, Ruggiero P, Grandi G, Fontana MR, Bensi G, Margarit I. Chiarot E, et al. Among authors: galletti b. Sci Rep. 2018 Feb 7;8(1):2593. doi: 10.1038/s41598-018-20609-5. Sci Rep. 2018. PMID: 29416049 Free PMC article.
Four-component Staphylococcus aureus vaccine 4C-staph enhances Fcγ receptor expression in neutrophils and monocytes and mitigates S. aureus infection in neutropenic mice.
Torre A, Bacconi M, Sammicheli C, Galletti B, Laera D, Fontana MR, Grandi G, De Gregorio E, Bagnoli F, Nuti S, Bertholet S, Bensi G. Torre A, et al. Among authors: galletti b. Infect Immun. 2015 Aug;83(8):3157-63. doi: 10.1128/IAI.00258-15. Epub 2015 May 26. Infect Immun. 2015. PMID: 26015481 Free PMC article.
MF59- and Al(OH)3-Adjuvanted Staphylococcus aureus (4C-Staph) Vaccines Induce Sustained Protective Humoral and Cellular Immune Responses, with a Critical Role for Effector CD4 T Cells at Low Antibody Titers.
Monaci E, Mancini F, Lofano G, Bacconi M, Tavarini S, Sammicheli C, Arcidiacono L, Giraldi M, Galletti B, Rossi Paccani S, Torre A, Fontana MR, Grandi G, de Gregorio E, Bensi G, Chiarot E, Nuti S, Bagnoli F, Soldaini E, Bertholet S. Monaci E, et al. Among authors: galletti b. Front Immunol. 2015 Sep 7;6:439. doi: 10.3389/fimmu.2015.00439. eCollection 2015. Front Immunol. 2015. PMID: 26441955 Free PMC article.
113 results