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The stereoselective targeting of a specific enzyme-substrate complex is the molecular mechanism for the synergic inhibition of HIV-1 reverse transcriptase by (R)-(-)-PPO464: a novel generation of nonnucleoside inhibitors.
Maga G, Ramunno A, Nacci V, Locatelli GA, Spadari S, Fiorini I, Baldanti F, Paolucci S, Zavattoni M, Bergamini A, Galletti B, Muck S, Hubscher U, Giorgi G, Guiso G, Caccia S, Campiani G. Maga G, et al. Among authors: galletti b. J Biol Chem. 2001 Nov 30;276(48):44653-62. doi: 10.1074/jbc.M106702200. Epub 2001 Sep 25. J Biol Chem. 2001. PMID: 11572864 Free article.
Specific targeting of highly conserved residues in the HIV-1 reverse transcriptase primer grip region. 2. Stereoselective interaction to overcome the effects of drug resistant mutations.
Butini S, Brindisi M, Cosconati S, Marinelli L, Borrelli G, Coccone SS, Ramunno A, Campiani G, Novellino E, Zanoli S, Samuele A, Giorgi G, Bergamini A, Di Mattia M, Lalli S, Galletti B, Gemma S, Maga G. Butini S, et al. Among authors: galletti b. J Med Chem. 2009 Feb 26;52(4):1224-8. doi: 10.1021/jm801395v. J Med Chem. 2009. PMID: 19170521
Pyrrolo[1,3]benzothiazepine-based atypical antipsychotic agents. Synthesis, structure-activity relationship, molecular modeling, and biological studies.
Campiani G, Butini S, Gemma S, Nacci V, Fattorusso C, Catalanotti B, Giorgi G, Cagnotto A, Goegan M, Mennini T, Minetti P, Di Cesare MA, Mastroianni D, Scafetta N, Galletti B, Stasi MA, Castorina M, Pacifici L, Ghirardi O, Tinti O, Carminati P. Campiani G, et al. Among authors: galletti b. J Med Chem. 2002 Jan 17;45(2):344-59. doi: 10.1021/jm010982y. J Med Chem. 2002. PMID: 11784139
Pyrrolo[1,3]benzothiazepine-based serotonin and dopamine receptor antagonists. Molecular modeling, further structure-activity relationship studies, and identification of novel atypical antipsychotic agents.
Campiani G, Butini S, Fattorusso C, Catalanotti B, Gemma S, Nacci V, Morelli E, Cagnotto A, Mereghetti I, Mennini T, Carli M, Minetti P, Di Cesare MA, Mastroianni D, Scafetta N, Galletti B, Stasi MA, Castorina M, Pacifici L, Vertechy M, Di Serio S, Ghirardi O, Tinti O, Carminati P. Campiani G, et al. Among authors: galletti b. J Med Chem. 2004 Jan 1;47(1):143-57. doi: 10.1021/jm0309811. J Med Chem. 2004. PMID: 14695828
On-column epimerization of dihydroartemisinin: an effective analytical approach to overcome the shortcomings of the International Pharmacopoeia monograph.
Cabri W, Ciogli A, D'Acquarica I, Di Mattia M, Galletti B, Gasparrini F, Giorgi F, Lalli S, Pierini M, Simone P. Cabri W, et al. Among authors: galletti b. J Chromatogr B Analyt Technol Biomed Life Sci. 2008 Nov 1;875(1):180-91. doi: 10.1016/j.jchromb.2008.06.037. J Chromatogr B Analyt Technol Biomed Life Sci. 2008. PMID: 18617445
Enantio- and chemo-selective HPLC separations by chiral-achiral tandem-columns approach: the combination of CHIROBIOTIC TAG and SCX columns for the analysis of propionyl carnitine and related impurities.
D'Acquarica I, Gasparrini F, Giannoli B, Badaloni E, Galletti B, Giorgi F, Tinti MO, Vigevani A. D'Acquarica I, et al. Among authors: galletti b. J Chromatogr A. 2004 Dec 24;1061(2):167-73. doi: 10.1016/j.chroma.2004.11.004. J Chromatogr A. 2004. PMID: 15641359
Identification of an isomer impurity in piperaquine drug substance.
Lindegårdh N, Giorgi F, Galletti B, Di Mattia M, Quaglia M, Carnevale D, White NJ, Mazzanti A, Day NP. Lindegårdh N, et al. Among authors: galletti b. J Chromatogr A. 2006 Dec 1;1135(2):166-9. doi: 10.1016/j.chroma.2006.09.066. Epub 2006 Oct 12. J Chromatogr A. 2006. PMID: 17046006
112 results