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Current methods to analyze lysosome morphology, positioning, motility and function.
Barral DC, Staiano L, Guimas Almeida C, Cutler DF, Eden ER, Futter CE, Galione A, Marques ARA, Medina DL, Napolitano G, Settembre C, Vieira OV, Aerts JMFG, Atakpa-Adaji P, Bruno G, Capuozzo A, De Leonibus E, Di Malta C, Escrevente C, Esposito A, Grumati P, Hall MJ, Teodoro RO, Lopes SS, Luzio JP, Monfregola J, Montefusco S, Platt FM, Polishchuck R, De Risi M, Sambri I, Soldati C, Seabra MC. Barral DC, et al. Among authors: galione a. Traffic. 2022 May;23(5):238-269. doi: 10.1111/tra.12839. Epub 2022 Apr 24. Traffic. 2022. PMID: 35343629 Free PMC article. Review.
Defective platelet function in Niemann-Pick disease type C1.
Chen OCW, Colaco A, Davis LC, Kiskin FN, Farhat NY, Speak AO, Smith DA, Morris L, Eden E, Tynan P, Churchill GC, Galione A, Porter FD, Platt FM. Chen OCW, et al. Among authors: galione a. JIMD Rep. 2020 Sep 12;56(1):46-57. doi: 10.1002/jmd2.12148. eCollection 2020 Nov. JIMD Rep. 2020. PMID: 33204596 Free PMC article.
Intracellular sphingosine releases calcium from lysosomes.
Höglinger D, Haberkant P, Aguilera-Romero A, Riezman H, Porter FD, Platt FM, Galione A, Schultz C. Höglinger D, et al. Among authors: galione a. Elife. 2015 Nov 27;4:e10616. doi: 10.7554/eLife.10616. Elife. 2015. PMID: 26613410 Free PMC article.
Purified TPC isoforms form NAADP receptors with distinct roles for Ca(2+) signaling and endolysosomal trafficking.
Ruas M, Rietdorf K, Arredouani A, Davis LC, Lloyd-Evans E, Koegel H, Funnell TM, Morgan AJ, Ward JA, Watanabe K, Cheng X, Churchill GC, Zhu MX, Platt FM, Wessel GM, Parrington J, Galione A. Ruas M, et al. Among authors: galione a. Curr Biol. 2010 Apr 27;20(8):703-9. doi: 10.1016/j.cub.2010.02.049. Epub 2010 Mar 25. Curr Biol. 2010. PMID: 20346675 Free PMC article.
Acetylation turns leucine into a drug by membrane transporter switching.
Churchill GC, Strupp M, Factor C, Bremova-Ertl T, Factor M, Patterson MC, Platt FM, Galione A. Churchill GC, et al. Among authors: galione a. Sci Rep. 2021 Aug 4;11(1):15812. doi: 10.1038/s41598-021-95255-5. Sci Rep. 2021. PMID: 34349180 Free PMC article.
238 results