Galic S - Search Results

1

Neuropeptide Y1 receptor antagonism protects β-cells and improves glycemic control in type 2 diabetes.

Yang CH, Ann-Onda D, Lin X, Fynch S, Nadarajah S, Pappas EG, Liu X, Scott JW, Oakhill JS, Galic S, Shi Y, Moreno-Asso A, Smith C, Loudovaris T, Levinger I, Eizirik DL, Laybutt DR, Herzog H, Thomas HE, Loh K. Yang CH, et al. Among authors: galic s. Mol Metab. 2022 Jan;55:101413. doi: 10.1016/j.molmet.2021.101413. Epub 2021 Dec 7. Mol Metab. 2022. PMID: 34890851 Free PMC article.

2

Reactive oxygen species enhance insulin sensitivity.

Loh K, Deng H, Fukushima A, Cai X, Boivin B, Galic S, Bruce C, Shields BJ, Skiba B, Ooms LM, Stepto N, Wu B, Mitchell CA, Tonks NK, Watt MJ, Febbraio MA, Crack PJ, Andrikopoulos S, Tiganis T. Loh K, et al. Among authors: galic s. Cell Metab. 2009 Oct;10(4):260-72. doi: 10.1016/j.cmet.2009.08.009. Cell Metab. 2009. PMID: 19808019 Free PMC article.

3

T-cell protein tyrosine phosphatase attenuates STAT3 and insulin signaling in the liver to regulate gluconeogenesis.

Fukushima A, Loh K, Galic S, Fam B, Shields B, Wiede F, Tremblay ML, Watt MJ, Andrikopoulos S, Tiganis T. Fukushima A, et al. Among authors: galic s. Diabetes. 2010 Aug;59(8):1906-14. doi: 10.2337/db09-1365. Epub 2010 May 18. Diabetes. 2010. PMID: 20484139 Free PMC article.

4

Liver-specific suppressor of cytokine signaling-3 deletion in mice enhances hepatic insulin sensitivity and lipogenesis resulting in fatty liver and obesity.

Sachithanandan N, Fam BC, Fynch S, Dzamko N, Watt MJ, Wormald S, Honeyman J, Galic S, Proietto J, Andrikopoulos S, Hevener AL, Kay TW, Steinberg GR. Sachithanandan N, et al. Among authors: galic s. Hepatology. 2010 Nov;52(5):1632-42. doi: 10.1002/hep.23861. Hepatology. 2010. PMID: 20799351

5

Macrophage deletion of SOCS1 increases sensitivity to LPS and palmitic acid and results in systemic inflammation and hepatic insulin resistance.

Sachithanandan N, Graham KL, Galic S, Honeyman JE, Fynch SL, Hewitt KA, Steinberg GR, Kay TW. Sachithanandan N, et al. Among authors: galic s. Diabetes. 2011 Aug;60(8):2023-31. doi: 10.2337/db11-0259. Epub 2011 Jun 6. Diabetes. 2011. PMID: 21646388 Free PMC article.

6

Elevated hypothalamic TCPTP in obesity contributes to cellular leptin resistance.

Loh K, Fukushima A, Zhang X, Galic S, Briggs D, Enriori PJ, Simonds S, Wiede F, Reichenbach A, Hauser C, Sims NA, Bence KK, Zhang S, Zhang ZY, Kahn BB, Neel BG, Andrews ZB, Cowley MA, Tiganis T. Loh K, et al. Among authors: galic s. Cell Metab. 2011 Nov 2;14(5):684-99. doi: 10.1016/j.cmet.2011.09.011. Epub 2011 Oct 13. Cell Metab. 2011. PMID: 22000926 Free PMC article.

7

T cell protein tyrosine phosphatase (TCPTP) deficiency in muscle does not alter insulin signalling and glucose homeostasis in mice.

Loh K, Merry TL, Galic S, Wu BJ, Watt MJ, Zhang S, Zhang ZY, Neel BG, Tiganis T. Loh K, et al. Among authors: galic s. Diabetologia. 2012 Feb;55(2):468-78. doi: 10.1007/s00125-011-2386-z. Epub 2011 Nov 29. Diabetologia. 2012. PMID: 22124607 Free PMC article.

8

Small molecule drug A-769662 and AMP synergistically activate naive AMPK independent of upstream kinase signaling.

Scott JW, Ling N, Issa SM, Dite TA, O'Brien MT, Chen ZP, Galic S, Langendorf CG, Steinberg GR, Kemp BE, Oakhill JS. Scott JW, et al. Among authors: galic s. Chem Biol. 2014 May 22;21(5):619-27. doi: 10.1016/j.chembiol.2014.03.006. Epub 2014 Apr 17. Chem Biol. 2014. PMID: 24746562

9

Inhibition of AMP-Activated Protein Kinase at the Allosteric Drug-Binding Site Promotes Islet Insulin Release.

Scott JW, Galic S, Graham KL, Foitzik R, Ling NX, Dite TA, Issa SM, Langendorf CG, Weng QP, Thomas HE, Kay TW, Birnberg NC, Steinberg GR, Kemp BE, Oakhill JS. Scott JW, et al. Among authors: galic s. Chem Biol. 2015 Jun 18;22(6):705-11. doi: 10.1016/j.chembiol.2015.05.011. Chem Biol. 2015. PMID: 26091167

10

The autophagy initiator ULK1 sensitizes AMPK to allosteric drugs.

Dite TA, Ling NXY, Scott JW, Hoque A, Galic S, Parker BL, Ngoei KRW, Langendorf CG, O'Brien MT, Kundu M, Viollet B, Steinberg GR, Sakamoto K, Kemp BE, Oakhill JS. Dite TA, et al. Among authors: galic s. Nat Commun. 2017 Sep 18;8(1):571. doi: 10.1038/s41467-017-00628-y. Nat Commun. 2017. PMID: 28924239 Free PMC article.

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