Regulation of BMP4/Dpp retrotranslocation and signaling by deglycosylation.
Galeone A, Adams JM, Matsuda S, Presa MF, Pandey A, Han SY, Tachida Y, Hirayama H, Vaccari T, Suzuki T, Lutz CM, Affolter M, Zuberi A, Jafar-Nejad H.
Galeone A, et al.
Elife. 2020 Jul 28;9:e55596. doi: 10.7554/eLife.55596.
Elife. 2020.
PMID: 32720893
Free PMC article.
We previously reported that NGLY1 regulates Drosophila BMP signaling in a tissue-specific manner (Galeone et al., 2017). Here, we establish the Drosophila Dpp and its mouse ortholog BMP4 as biologically relevant targets of NGLY1 and find, unexpectedly, that NGLY1-me …
We previously reported that NGLY1 regulates Drosophila BMP signaling in a tissue-specific manner (Galeone et al., 2017). Here, …