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Drug-tolerant persister cancer cells are vulnerable to GPX4 inhibition.
Hangauer MJ, Viswanathan VS, Ryan MJ, Bole D, Eaton JK, Matov A, Galeas J, Dhruv HD, Berens ME, Schreiber SL, McCormick F, McManus MT. Hangauer MJ, et al. Among authors: galeas j. Nature. 2017 Nov 9;551(7679):247-250. doi: 10.1038/nature24297. Epub 2017 Nov 1. Nature. 2017. PMID: 29088702 Free PMC article.
Aurora kinase A drives the evolution of resistance to third-generation EGFR inhibitors in lung cancer.
Shah KN, Bhatt R, Rotow J, Rohrberg J, Olivas V, Wang VE, Hemmati G, Martins MM, Maynard A, Kuhn J, Galeas J, Donnella HJ, Kaushik S, Ku A, Dumont S, Krings G, Haringsma HJ, Robillard L, Simmons AD, Harding TC, McCormick F, Goga A, Blakely CM, Bivona TG, Bandyopadhyay S. Shah KN, et al. Among authors: galeas j. Nat Med. 2019 Jan;25(1):111-118. doi: 10.1038/s41591-018-0264-7. Epub 2018 Nov 26. Nat Med. 2019. PMID: 30478424 Free PMC article.
Ras-GTP dimers activate the Mitogen-Activated Protein Kinase (MAPK) pathway.
Nan X, Tamgüney TM, Collisson EA, Lin LJ, Pitt C, Galeas J, Lewis S, Gray JW, McCormick F, Chu S. Nan X, et al. Among authors: galeas j. Proc Natl Acad Sci U S A. 2015 Jun 30;112(26):7996-8001. doi: 10.1073/pnas.1509123112. Epub 2015 Jun 16. Proc Natl Acad Sci U S A. 2015. PMID: 26080442 Free PMC article.
RIT1 oncoproteins escape LZTR1-mediated proteolysis.
Castel P, Cheng A, Cuevas-Navarro A, Everman DB, Papageorge AG, Simanshu DK, Tankka A, Galeas J, Urisman A, McCormick F. Castel P, et al. Among authors: galeas j. Science. 2019 Mar 15;363(6432):1226-1230. doi: 10.1126/science.aav1444. Science. 2019. PMID: 30872527 Free PMC article.
A snapshot of lung cancer: where are we now?-a narrative review.
Ibodeng GO, Uche IN, Mokua R, Galo M, Odigwe B, Galeas JN, Dasgupta S. Ibodeng GO, et al. Among authors: galeas jn. Ann Transl Med. 2023 Mar 31;11(6):261. doi: 10.21037/atm-22-4479. Epub 2023 Feb 6. Ann Transl Med. 2023. PMID: 37082671 Free PMC article. Review.
21 results