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Anti-norovirus therapeutics: a patent review (2010-2015).
Galasiti Kankanamalage AC, Weerawarna PM, Kim Y, Chang KO, Groutas WC. Galasiti Kankanamalage AC, et al. Expert Opin Ther Pat. 2016;26(3):297-308. doi: 10.1517/13543776.2016.1153065. Expert Opin Ther Pat. 2016. PMID: 26881878 Free PMC article. Review.
Structure-guided design and optimization of dipeptidyl inhibitors of norovirus 3CL protease. Structure-activity relationships and biochemical, X-ray crystallographic, cell-based, and in vivo studies.
Galasiti Kankanamalage AC, Kim Y, Weerawarna PM, Uy RA, Damalanka VC, Mandadapu SR, Alliston KR, Mehzabeen N, Battaile KP, Lovell S, Chang KO, Groutas WC. Galasiti Kankanamalage AC, et al. J Med Chem. 2015 Apr 9;58(7):3144-55. doi: 10.1021/jm5019934. Epub 2015 Mar 19. J Med Chem. 2015. PMID: 25761614 Free PMC article.
Recent Advances in the Discovery of Norovirus Therapeutics.
Kim Y, Galasiti Kankanamalage AC, Chang KO, Groutas WC. Kim Y, et al. J Med Chem. 2015 Dec 24;58(24):9438-50. doi: 10.1021/acs.jmedchem.5b00762. Epub 2015 Aug 17. J Med Chem. 2015. PMID: 26258852 Free PMC article. Review.
Structure-based design and synthesis of triazole-based macrocyclic inhibitors of norovirus protease: Structural, biochemical, spectroscopic, and antiviral studies.
Weerawarna PM, Kim Y, Galasiti Kankanamalage AC, Damalanka VC, Lushington GH, Alliston KR, Mehzabeen N, Battaile KP, Lovell S, Chang KO, Groutas WC. Weerawarna PM, et al. Eur J Med Chem. 2016 Aug 25;119:300-18. doi: 10.1016/j.ejmech.2016.04.013. Epub 2016 Apr 25. Eur J Med Chem. 2016. PMID: 27235842 Free PMC article.
Structure-based exploration and exploitation of the S4 subsite of norovirus 3CL protease in the design of potent and permeable inhibitors.
Galasiti Kankanamalage AC, Kim Y, Rathnayake AD, Damalanka VC, Weerawarna PM, Doyle ST, Alsoudi AF, Dissanayake DMP, Lushington GH, Mehzabeen N, Battaile KP, Lovell S, Chang KO, Groutas WC. Galasiti Kankanamalage AC, et al. Eur J Med Chem. 2017 Jan 27;126:502-516. doi: 10.1016/j.ejmech.2016.11.027. Epub 2016 Nov 14. Eur J Med Chem. 2017. PMID: 27914364 Free PMC article.
Structure-guided design, synthesis and evaluation of oxazolidinone-based inhibitors of norovirus 3CL protease.
Damalanka VC, Kim Y, Galasiti Kankanamalage AC, Rathnayake AD, Mehzabeen N, Battaile KP, Lovell S, Nguyen HN, Lushington GH, Chang KO, Groutas WC. Damalanka VC, et al. Among authors: galasiti kankanamalage ac. Eur J Med Chem. 2018 Jan 1;143:881-890. doi: 10.1016/j.ejmech.2017.12.014. Epub 2017 Dec 6. Eur J Med Chem. 2018. PMID: 29227928 Free PMC article.
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