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Characterization and use of Equine Bone Marrow Mesenchymal Stem Cells in Equine Cartilage Engineering. Study of their Hyaline Cartilage Forming Potential when Cultured under Hypoxia within a Biomaterial in the Presence of BMP-2 and TGF-ß1.
Branly T, Bertoni L, Contentin R, Rakic R, Gomez-Leduc T, Desancé M, Hervieu M, Legendre F, Jacquet S, Audigié F, Denoix JM, Demoor M, Galéra P. Branly T, et al. Among authors: galera p. Stem Cell Rev Rep. 2017 Oct;13(5):611-630. doi: 10.1007/s12015-017-9748-y. Stem Cell Rev Rep. 2017. PMID: 28597211
Interleukin-6 (IL-6) and/or soluble IL-6 receptor down-regulation of human type II collagen gene expression in articular chondrocytes requires a decrease of Sp1.Sp3 ratio and of the binding activity of both factors to the COL2A1 promoter.
Porée B, Kypriotou M, Chadjichristos C, Beauchef G, Renard E, Legendre F, Melin M, Gueret S, Hartmann DJ, Malléin-Gerin F, Pujol JP, Boumediene K, Galéra P. Porée B, et al. Among authors: galera p. J Biol Chem. 2008 Feb 22;283(8):4850-65. doi: 10.1074/jbc.M706387200. Epub 2007 Dec 7. J Biol Chem. 2008. PMID: 18065760 Free article.
Hypoxia-inducible factor 1alpha inhibits the fibroblast-like markers type I and type III collagen during hypoxia-induced chondrocyte redifferentiation: hypoxia not only induces type II collagen and aggrecan, but it also inhibits type I and type III collagen in the hypoxia-inducible factor 1alpha-dependent redifferentiation of chondrocytes.
Duval E, Leclercq S, Elissalde JM, Demoor M, Galéra P, Boumédiene K. Duval E, et al. Among authors: galera p. Arthritis Rheum. 2009 Oct;60(10):3038-48. doi: 10.1002/art.24851. Arthritis Rheum. 2009. PMID: 19790048 Free article.
Asporin expression is highly regulated in human chondrocytes.
Duval E, Bigot N, Hervieu M, Kou I, Leclercq S, Galéra P, Boumediene K, Baugé C. Duval E, et al. Among authors: galera p. Mol Med. 2011;17(7-8):816-23. doi: 10.2119/molmed.2011.00052. Epub 2011 Apr 25. Mol Med. 2011. PMID: 21528154 Free PMC article.
The p65 subunit of NF-κB inhibits COL1A1 gene transcription in human dermal and scleroderma fibroblasts through its recruitment on promoter by protein interaction with transcriptional activators (c-Krox, Sp1, and Sp3).
Beauchef G, Bigot N, Kypriotou M, Renard E, Porée B, Widom R, Dompmartin-Blanchere A, Oddos T, Maquart FX, Demoor M, Boumediene K, Galera P. Beauchef G, et al. Among authors: galera p. J Biol Chem. 2012 Jan 27;287(5):3462-78. doi: 10.1074/jbc.M111.286443. Epub 2011 Dec 2. J Biol Chem. 2012. PMID: 22139845 Free PMC article.
138 results