Gaj S - Search Results

1

The exposome concept in a human nutrigenomics study: evaluating the impact of exposure to a complex mixture of phytochemicals using transcriptomics signatures.

van Breda SG, Wilms LC, Gaj S, Jennen DG, Briedé JJ, Kleinjans JC, de Kok TM. van Breda SG, et al. Among authors: gaj s. Mutagenesis. 2015 Nov;30(6):723-31. doi: 10.1093/mutage/gev008. Epub 2015 Feb 22. Mutagenesis. 2015. PMID: 25711498 Review.

2

Can transcriptomics provide insight into the chemopreventive mechanisms of complex mixtures of phytochemicals in humans?

van Breda SG, Wilms LC, Gaj S, Jennen DG, Briedé JJ, Helsper JP, Kleinjans JC, de Kok TM. van Breda SG, et al. Among authors: gaj s. Antioxid Redox Signal. 2014 May 10;20(14):2107-13. doi: 10.1089/ars.2013.5528. Epub 2014 Feb 27. Antioxid Redox Signal. 2014. PMID: 24328558 Free PMC article. Clinical Trial.

3

'Omics analysis of low dose acetaminophen intake demonstrates novel response pathways in humans.

Jetten MJ, Gaj S, Ruiz-Aracama A, de Kok TM, van Delft JH, Lommen A, van Someren EP, Jennen DG, Claessen SM, Peijnenburg AA, Stierum RH, Kleinjans JC. Jetten MJ, et al. Among authors: gaj s. Toxicol Appl Pharmacol. 2012 Mar 15;259(3):320-8. doi: 10.1016/j.taap.2012.01.009. Epub 2012 Jan 20. Toxicol Appl Pharmacol. 2012. PMID: 22285215 Clinical Trial.

4

Evaluation of database-derived pathway development for enabling biomarker discovery for hepatotoxicity.

Hebels DG, Jetten MJ, Aerts HJ, Herwig R, Theunissen DH, Gaj S, van Delft JH, Kleinjans JC. Hebels DG, et al. Among authors: gaj s. Biomark Med. 2014;8(2):185-200. doi: 10.2217/bmm.13.154. Biomark Med. 2014. PMID: 24521014 Free article. Review.

5

Epigenetic mechanisms underlying arsenic-associated lung carcinogenesis.

van Breda SG, Claessen SM, Lo K, van Herwijnen M, Brauers KJ, Lisanti S, Theunissen DH, Jennen DG, Gaj S, de Kok TM, Kleinjans JC. van Breda SG, et al. Among authors: gaj s. Arch Toxicol. 2015 Nov;89(11):1959-69. doi: 10.1007/s00204-014-1351-2. Epub 2014 Sep 9. Arch Toxicol. 2015. PMID: 25199682

6

Integrating multiple omics to unravel mechanisms of Cyclosporin A induced hepatotoxicity in vitro.

Van den Hof WF, Ruiz-Aracama A, Van Summeren A, Jennen DG, Gaj S, Coonen ML, Brauers K, Wodzig WK, van Delft JH, Kleinjans JC. Van den Hof WF, et al. Among authors: gaj s. Toxicol In Vitro. 2015 Apr;29(3):489-501. doi: 10.1016/j.tiv.2014.12.016. Epub 2015 Jan 3. Toxicol In Vitro. 2015. PMID: 25562108

7

High-throughput data integration of RNA-miRNA-circRNA reveals novel insights into mechanisms of benzo[a]pyrene-induced carcinogenicity.

Caiment F, Gaj S, Claessen S, Kleinjans J. Caiment F, et al. Among authors: gaj s. Nucleic Acids Res. 2015 Mar 11;43(5):2525-34. doi: 10.1093/nar/gkv115. Epub 2015 Feb 17. Nucleic Acids Res. 2015. PMID: 25690898 Free PMC article.

8

RNA-Seq provides new insights in the transcriptome responses induced by the carcinogen benzo[a]pyrene.

van Delft J, Gaj S, Lienhard M, Albrecht MW, Kirpiy A, Brauers K, Claessen S, Lizarraga D, Lehrach H, Herwig R, Kleinjans J. van Delft J, et al. Among authors: gaj s. Toxicol Sci. 2012 Dec;130(2):427-39. doi: 10.1093/toxsci/kfs250. Epub 2012 Aug 13. Toxicol Sci. 2012. PMID: 22889811

9

Biotransformation pathway maps in WikiPathways enable direct visualization of drug metabolism related expression changes.

Jennen DG, Gaj S, Giesbertz PJ, van Delft JH, Evelo CT, Kleinjans JC. Jennen DG, et al. Among authors: gaj s. Drug Discov Today. 2010 Oct;15(19-20):851-8. doi: 10.1016/j.drudis.2010.08.002. Epub 2010 Aug 11. Drug Discov Today. 2010. PMID: 20708095 Review.

10

Benzo[a]pyrene-induced changes in microRNA-mRNA networks.

Lizarraga D, Gaj S, Brauers KJ, Timmermans L, Kleinjans JC, van Delft JH. Lizarraga D, et al. Among authors: gaj s. Chem Res Toxicol. 2012 Apr 16;25(4):838-49. doi: 10.1021/tx2003799. Epub 2012 Feb 22. Chem Res Toxicol. 2012. PMID: 22316170

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