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The C-Terminal Domain of LRRK2 with the G2019S Substitution Increases Mutant A53T α-Synuclein Toxicity in Dopaminergic Neurons In Vivo.
Cresto N, Gardier C, Gaillard MC, Gubinelli F, Roost P, Molina D, Josephine C, Dufour N, Auregan G, Guillermier M, Bernier S, Jan C, Gipchtein P, Hantraye P, Chartier-Harlin MC, Bonvento G, Van Camp N, Taymans JM, Cambon K, Liot G, Bemelmans AP, Brouillet E. Cresto N, et al. Among authors: gaillard mc. Int J Mol Sci. 2021 Jun 23;22(13):6760. doi: 10.3390/ijms22136760. Int J Mol Sci. 2021. PMID: 34201785 Free PMC article.
Dopamine determines the vulnerability of striatal neurons to the N-terminal fragment of mutant huntingtin through the regulation of mitochondrial complex II.
Benchoua A, Trioulier Y, Diguet E, Malgorn C, Gaillard MC, Dufour N, Elalouf JM, Krajewski S, Hantraye P, Déglon N, Brouillet E. Benchoua A, et al. Among authors: gaillard mc. Hum Mol Genet. 2008 May 15;17(10):1446-56. doi: 10.1093/hmg/ddn033. Epub 2008 Feb 11. Hum Mol Genet. 2008. PMID: 18267960 Free PMC article.
Capucin does not modify the toxicity of a mutant Huntingtin fragment in vivo.
Galvan L, Lepejová N, Gaillard MC, Malgorn C, Guillermier M, Houitte D, Bonvento G, Petit F, Dufour N, Héry P, Gérard M, Elalouf JM, Déglon N, Brouillet E, de Chaldée M. Galvan L, et al. Among authors: gaillard mc. Neurobiol Aging. 2012 Aug;33(8):1845.e5-6. doi: 10.1016/j.neurobiolaging.2012.01.009. Epub 2012 Feb 24. Neurobiol Aging. 2012. PMID: 22365050
IRC-082451, a novel multitargeting molecule, reduces L-DOPA-induced dyskinesias in MPTP Parkinsonian primates.
Aron Badin R, Spinnewyn B, Gaillard MC, Jan C, Malgorn C, Van Camp N, Dollé F, Guillermier M, Boulet S, Bertrand A, Savasta M, Auguet M, Brouillet E, Chabrier PE, Hantraye P. Aron Badin R, et al. Among authors: gaillard mc. PLoS One. 2013;8(1):e52680. doi: 10.1371/journal.pone.0052680. Epub 2013 Jan 3. PLoS One. 2013. PMID: 23300984 Free PMC article.
SET translocation is associated with increase in caspase cleaved amyloid precursor protein in CA1 of Alzheimer and Down syndrome patients.
Facchinetti P, Dorard E, Contremoulins V, Gaillard MC, Déglon N, Sazdovitch V, Guihenneuc-Jouyaux C, Brouillet E, Duyckaerts C, Allinquant B. Facchinetti P, et al. Among authors: gaillard mc. Neurobiol Aging. 2014 May;35(5):958-68. doi: 10.1016/j.neurobiolaging.2013.08.039. Epub 2013 Nov 5. Neurobiol Aging. 2014. PMID: 24262202
Impaired brain energy metabolism in the BACHD mouse model of Huntington's disease: critical role of astrocyte-neuron interactions.
Boussicault L, Hérard AS, Calingasan N, Petit F, Malgorn C, Merienne N, Jan C, Gaillard MC, Lerchundi R, Barros LF, Escartin C, Delzescaux T, Mariani J, Hantraye P, Beal MF, Brouillet E, Véga C, Bonvento G. Boussicault L, et al. Among authors: gaillard mc. J Cereb Blood Flow Metab. 2014 Sep;34(9):1500-10. doi: 10.1038/jcbfm.2014.110. Epub 2014 Jun 18. J Cereb Blood Flow Metab. 2014. PMID: 24938402 Free PMC article.
Loss of the thyroid hormone-binding protein Crym renders striatal neurons more vulnerable to mutant huntingtin in Huntington's disease.
Francelle L, Galvan L, Gaillard MC, Guillermier M, Houitte D, Bonvento G, Petit F, Jan C, Dufour N, Hantraye P, Elalouf JM, De Chaldée M, Déglon N, Brouillet E. Francelle L, et al. Among authors: gaillard mc. Hum Mol Genet. 2015 Mar 15;24(6):1563-73. doi: 10.1093/hmg/ddu571. Epub 2014 Nov 14. Hum Mol Genet. 2015. PMID: 25398949 Free PMC article.
Striatal long noncoding RNA Abhd11os is neuroprotective against an N-terminal fragment of mutant huntingtin in vivo.
Francelle L, Galvan L, Gaillard MC, Petit F, Bernay B, Guillermier M, Bonvento G, Dufour N, Elalouf JM, Hantraye P, Déglon N, de Chaldée M, Brouillet E. Francelle L, et al. Among authors: gaillard mc. Neurobiol Aging. 2015 Mar;36(3):1601.e7-16. doi: 10.1016/j.neurobiolaging.2014.11.014. Epub 2014 Dec 18. Neurobiol Aging. 2015. PMID: 25619660 Free article.
119 results