Gaikwad SM - Search Results

1

A Small Molecule Stabilizer of the MYC G4-Quadruplex Induces Endoplasmic Reticulum Stress, Senescence and Pyroptosis in Multiple Myeloma.

Gaikwad SM, Phyo Z, Arteaga AQ, Gorjifard S, Calabrese DR, Connors D, Huang J, Michalowski AM, Zhang S, Liu ZG, Schneekloth JS Jr, Mock BA. Gaikwad SM, et al. Cancers (Basel). 2020 Oct 13;12(10):2952. doi: 10.3390/cancers12102952. Cancers (Basel). 2020. PMID: 33066043 Free PMC article.

2

Chemical and structural studies provide a mechanistic basis for recognition of the MYC G-quadruplex.

Calabrese DR, Chen X, Leon EC, Gaikwad SM, Phyo Z, Hewitt WM, Alden S, Hilimire TA, He F, Michalowski AM, Simmons JK, Saunders LB, Zhang S, Connors D, Walters KJ, Mock BA, Schneekloth JS Jr. Calabrese DR, et al. Among authors: gaikwad sm. Nat Commun. 2018 Oct 12;9(1):4229. doi: 10.1038/s41467-018-06315-w. Nat Commun. 2018. PMID: 30315240 Free PMC article.

3

Characterization of clinically used oral antiseptics as quadruplex-binding ligands.

Calabrese DR, Zlotkowski K, Alden S, Hewitt WM, Connelly CM, Wilson RM, Gaikwad S, Chen L, Guha R, Thomas CJ, Mock BA, Schneekloth JS Jr. Calabrese DR, et al. Nucleic Acids Res. 2018 Apr 6;46(6):2722-2732. doi: 10.1093/nar/gky084. Nucleic Acids Res. 2018. PMID: 29481610 Free PMC article.

4

Mouse tumor susceptibility genes identify drug combinations for multiple myeloma.

Zhang S, DuBois W, Zhang K, Simmons JK, Hughitt VK, Gorjifard S, Gaikwad S, Peat TJ, Mock BA. Zhang S, et al. J Cancer Metastasis Treat. 2020;6:21. doi: 10.20517/2394-4722.2020.40. Epub 2020 Jul 26. J Cancer Metastasis Treat. 2020. PMID: 32923678 Free PMC article.

5

Cooperative Targets of Combined mTOR/HDAC Inhibition Promote MYC Degradation.

Simmons JK, Michalowski AM, Gamache BJ, DuBois W, Patel J, Zhang K, Gary J, Zhang S, Gaikwad S, Connors D, Watson N, Leon E, Chen JQ, Kuehl WM, Lee MP, Zingone A, Landgren O, Ordentlich P, Huang J, Mock BA. Simmons JK, et al. Mol Cancer Ther. 2017 Sep;16(9):2008-2021. doi: 10.1158/1535-7163.MCT-17-0171. Epub 2017 May 18. Mol Cancer Ther. 2017. PMID: 28522584 Free PMC article.

6

Hypomorphic mTOR Downregulates CDK6 and Delays Thymic Pre-T LBL Tumorigenesis.

Gary JM, Simmons JK, Xu J, Zhang S, Peat TJ, Watson N, Gamache BJ, Zhang K, Kovalchuk AL, Michalowski AM, Chen JQ, Thaiwong T, Kiupel M, Gaikwad S, Etienne M, Simpson RM, Dubois W, Testa JR, Mock BA. Gary JM, et al. Mol Cancer Ther. 2020 Oct;19(10):2221-2232. doi: 10.1158/1535-7163.MCT-19-0671. Epub 2020 Aug 3. Mol Cancer Ther. 2020. PMID: 32747423 Free PMC article.

7

IGF-1R inhibition potentiates cytotoxic effects of chemotherapeutic agents in early stages of chemoresistant ovarian cancer cells.

Singh RK, Gaikwad SM, Jinager A, Chaudhury S, Maheshwari A, Ray P. Singh RK, et al. Among authors: gaikwad sm. Cancer Lett. 2014 Nov 28;354(2):254-62. doi: 10.1016/j.canlet.2014.08.023. Epub 2014 Aug 23. Cancer Lett. 2014. PMID: 25157649

8

Differential activation of NF-κB signaling is associated with platinum and taxane resistance in MyD88 deficient epithelial ovarian cancer cells.

Gaikwad SM, Thakur B, Sakpal A, Singh RK, Ray P. Gaikwad SM, et al. Int J Biochem Cell Biol. 2015 Apr;61:90-102. doi: 10.1016/j.biocel.2015.02.001. Epub 2015 Feb 11. Int J Biochem Cell Biol. 2015. PMID: 25681684

9

Soft drug-resistant ovarian cancer cells migrate via two distinct mechanisms utilizing myosin II-based contractility.

Kapoor A, Barai A, Thakur B, Das A, Patwardhan SR, Monteiro M, Gaikwad S, Bukhari AB, Mogha P, Majumder A, De A, Ray P, Sen S. Kapoor A, et al. Biochim Biophys Acta Mol Cell Res. 2018 Feb;1865(2):392-405. doi: 10.1016/j.bbamcr.2017.11.012. Epub 2017 Nov 22. Biochim Biophys Acta Mol Cell Res. 2018. PMID: 29175377 Free article.

10

Non-invasive imaging of PI3K/Akt/mTOR signalling in cancer.

Gaikwad SM, Ray P. Gaikwad SM, et al. Am J Nucl Med Mol Imaging. 2012;2(4):418-31. Epub 2012 Oct 15. Am J Nucl Med Mol Imaging. 2012. PMID: 23145359 Free PMC article.

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