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Treatment with hyperimmune equine immunoglobulin or immunoglobulin fragments completely protects rodents from Ebola virus infection.
Zheng X, Wong G, Zhao Y, Wang H, He S, Bi Y, Chen W, Jin H, Gai W, Chu D, Cao Z, Wang C, Fan Q, Chi H, Gao Y, Wang T, Feng N, Yan F, Huang G, Zheng Y, Li N, Li Y, Qian J, Zou Y, Kobinger G, Gao GF, Qiu X, Yang S, Xia X. Zheng X, et al. Among authors: gai w. Sci Rep. 2016 Apr 12;6:24179. doi: 10.1038/srep24179. Sci Rep. 2016. PMID: 27067649 Free PMC article.
Passive immunotherapy for Middle East Respiratory Syndrome coronavirus infection with equine immunoglobulin or immunoglobulin fragments in a mouse model.
Zhao Y, Wang C, Qiu B, Li C, Wang H, Jin H, Gai W, Zheng X, Wang T, Sun W, Yan F, Gao Y, Wang Q, Yan J, Chen L, Perlman S, Zhong N, Zhao J, Yang S, Xia X. Zhao Y, et al. Among authors: gai w. Antiviral Res. 2017 Jan;137:125-130. doi: 10.1016/j.antiviral.2016.11.016. Epub 2016 Nov 24. Antiviral Res. 2017. PMID: 27890674 Free PMC article.
Equine-Origin Immunoglobulin Fragments Protect Nonhuman Primates from Ebola Virus Disease.
Wang H, Wong G, Zhu W, He S, Zhao Y, Yan F, Rahim MN, Bi Y, Zhang Z, Cheng K, Jin H, Cao Z, Zheng X, Gai W, Bai J, Chen W, Zou Y, Gao Y, Gao GF, Yang S, Xia X, Qiu X. Wang H, et al. Among authors: gai w. J Virol. 2019 Feb 19;93(5):e01548-18. doi: 10.1128/JVI.01548-18. Print 2019 Mar 1. J Virol. 2019. PMID: 30541860 Free PMC article.
Novel chimeric virus-like particles vaccine displaying MERS-CoV receptor-binding domain induce specific humoral and cellular immune response in mice.
Wang C, Zheng X, Gai W, Wong G, Wang H, Jin H, Feng N, Zhao Y, Zhang W, Li N, Zhao G, Li J, Yan J, Gao Y, Hu G, Yang S, Xia X. Wang C, et al. Among authors: gai w. Antiviral Res. 2017 Apr;140:55-61. doi: 10.1016/j.antiviral.2016.12.019. Epub 2016 Dec 28. Antiviral Res. 2017. PMID: 28040513 Free PMC article.
278 results