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Early decrease of blood myeloid-derived suppressor cells during checkpoint inhibition is a favorable biomarker in metastatic melanoma.
Gaißler A, Bochem J, Spreuer J, Ottmann S, Martens A, Amaral T, Wagner NB, Claassen M, Meier F, Terheyden P, Garbe C, Eigentler T, Weide B, Pawelec G, Wistuba-Hamprecht K. Gaißler A, et al. J Immunother Cancer. 2023 Jun;11(6):e006802. doi: 10.1136/jitc-2023-006802. J Immunother Cancer. 2023. PMID: 37286306 Free PMC article.
Early disappearance of tumor antigen-reactive T cells from peripheral blood correlates with superior clinical outcomes in melanoma under anti-PD-1 therapy.
Bochem J, Zelba H, Spreuer J, Amaral T, Wagner NB, Gaissler A, Pop OT, Thiel K, Yurttas C, Soffel D, Forchhammer S, Sinnberg T, Niessner H, Meier F, Terheyden P, Königsrainer A, Garbe C, Flatz L, Pawelec G, Eigentler TK, Löffler MW, Weide B, Wistuba-Hamprecht K. Bochem J, et al. Among authors: gaissler a. J Immunother Cancer. 2021 Dec;9(12):e003439. doi: 10.1136/jitc-2021-003439. J Immunother Cancer. 2021. PMID: 34933966 Free PMC article.
Dynamics of Melanoma-Associated Epitope-Specific CD8+ T Cells in the Blood Correlate With Clinical Outcome Under PD-1 Blockade.
Gaißler A, Meldgaard TS, Heeke C, Babaei S, Tvingsholm SA, Bochem J, Spreuer J, Amaral T, Wagner NB, Klein R, Meier F, Garbe C, Eigentler TK, Pawelec G, Claassen M, Weide B, Hadrup SR, Wistuba-Hamprecht K. Gaißler A, et al. Front Immunol. 2022 Jul 7;13:906352. doi: 10.3389/fimmu.2022.906352. eCollection 2022. Front Immunol. 2022. PMID: 35874702 Free PMC article.
ATF3 characterizes aggressive drug-tolerant persister cells in HGSOC.
Böpple K, Oren Y, Henry WS, Dong M, Weller S, Thiel J, Kleih M, Gaißler A, Zipperer D, Kopp HG, Aylon Y, Oren M, Essmann F, Liang C, Aulitzky WE. Böpple K, et al. Among authors: gaissler a. Cell Death Dis. 2024 Apr 24;15(4):290. doi: 10.1038/s41419-024-06674-x. Cell Death Dis. 2024. PMID: 38658567 Free PMC article.