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Inhibition of ERK5 Elicits Cellular Senescence in Melanoma via the Cyclin-Dependent Kinase Inhibitor p21.
Tubita A, Lombardi Z, Tusa I, Lazzeretti A, Sgrignani G, Papini D, Menconi A, Gagliardi S, Lulli M, Dello Sbarba P, Esparís-Ogando A, Pandiella A, Stecca B, Rovida E. Tubita A, et al. Among authors: gagliardi s. Cancer Res. 2022 Feb 1;82(3):447-457. doi: 10.1158/0008-5472.CAN-21-0993. Epub 2021 Nov 19. Cancer Res. 2022. PMID: 34799355 Free PMC article.
ERK5 is activated by oncogenic BRAF and promotes melanoma growth.
Tusa I, Gagliardi S, Tubita A, Pandolfi S, Urso C, Borgognoni L, Wang J, Deng X, Gray NS, Stecca B, Rovida E. Tusa I, et al. Among authors: gagliardi s. Oncogene. 2018 May;37(19):2601-2614. doi: 10.1038/s41388-018-0164-9. Epub 2018 Feb 27. Oncogene. 2018. PMID: 29483645 Free PMC article.
Targeting non-canonical activation of GLI1 by the SOX2-BRD4 transcriptional complex improves the efficacy of HEDGEHOG pathway inhibition in melanoma.
Pietrobono S, Gaudio E, Gagliardi S, Zitani M, Carrassa L, Migliorini F, Petricci E, Manetti F, Makukhin N, Bond AG, Paradise BD, Ciulli A, Fernandez-Zapico ME, Bertoni F, Stecca B. Pietrobono S, et al. Among authors: gagliardi s. Oncogene. 2021 Jun;40(22):3799-3814. doi: 10.1038/s41388-021-01783-9. Epub 2021 May 6. Oncogene. 2021. PMID: 33958721 Free PMC article.
Targeted inhibition of Hedgehog-GLI signaling by novel acylguanidine derivatives inhibits melanoma cell growth by inducing replication stress and mitotic catastrophe.
Pietrobono S, Santini R, Gagliardi S, Dapporto F, Colecchia D, Chiariello M, Leone C, Valoti M, Manetti F, Petricci E, Taddei M, Stecca B. Pietrobono S, et al. Among authors: gagliardi s. Cell Death Dis. 2018 Feb 2;9(2):142. doi: 10.1038/s41419-017-0142-0. Cell Death Dis. 2018. PMID: 29396391 Free PMC article.
Extracellular vesicles secreted by cumulus cells contain microRNAs that are potential regulatory factors of mouse oocyte developmental competence.
Fiorentino G, Merico V, Zanoni M, Comincini S, Sproviero D, Garofalo M, Gagliardi S, Cereda C, Lin CJ, Innocenti F, Taggi M, Vaiarelli A, Ubaldi FM, Rienzi L, Cimadomo D, Garagna S, Zuccotti M. Fiorentino G, et al. Among authors: gagliardi s. Mol Hum Reprod. 2024 May 14:gaae019. doi: 10.1093/molehr/gaae019. Online ahead of print. Mol Hum Reprod. 2024. PMID: 38745364
233 results