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A plausibly causal functional lupus-associated risk variant in the STAT1-STAT4 locus.
Patel ZH, Lu X, Miller D, Forney CR, Lee J, Lynch A, Schroeder C, Parks L, Magnusen AF, Chen X, Pujato M, Maddox A, Zoller EE, Namjou B, Brunner HI, Henrickson M, Huggins JL, Williams AH, Ziegler JT, Comeau ME, Marion MC, Glenn SB, Adler A, Shen N, Nath SK, Stevens AM, Freedman BI, Pons-Estel BA, Tsao BP, Jacob CO, Kamen DL, Brown EE, Gilkeson GS, Alarcón GS, Martin J, Reveille JD, Anaya JM, James JA, Sivils KL, Criswell LA, Vilá LM, Petri M, Scofield RH, Kimberly RP, Edberg JC, Ramsey-Goldman R, Bang SY, Lee HS, Bae SC, Boackle SA, Cunninghame Graham D, Vyse TJ, Merrill JT, Niewold TB, Ainsworth HC, Silverman ED, Weisman MH, Wallace DJ, Raj P, Guthridge JM, Gaffney PM, Kelly JA, Alarcón-Riquelme ME, Langefeld CD, Wakeland EK, Kaufman KM, Weirauch MT, Harley JB, Kottyan LC. Patel ZH, et al. Among authors: gaffney pm. Hum Mol Genet. 2018 Jul 1;27(13):2392-2404. doi: 10.1093/hmg/ddy140. Hum Mol Genet. 2018. PMID: 29912393 Free PMC article. Clinical Trial.
The genetics of human systemic lupus erythematosus.
Harley JB, Moser KL, Gaffney PM, Behrens TW. Harley JB, et al. Among authors: gaffney pm. Curr Opin Immunol. 1998 Dec;10(6):690-6. doi: 10.1016/s0952-7915(98)80090-3. Curr Opin Immunol. 1998. PMID: 9914226 Review.
Visualizing human leukocyte antigen class II risk haplotypes in human systemic lupus erythematosus.
Graham RR, Ortmann WA, Langefeld CD, Jawaheer D, Selby SA, Rodine PR, Baechler EC, Rohlf KE, Shark KB, Espe KJ, Green LE, Nair RP, Stuart PE, Elder JT, King RA, Moser KL, Gaffney PM, Bugawan TL, Erlich HA, Rich SS, Gregersen PK, Behrens TW. Graham RR, et al. Among authors: gaffney pm. Am J Hum Genet. 2002 Sep;71(3):543-53. doi: 10.1086/342290. Epub 2002 Jul 26. Am J Hum Genet. 2002. PMID: 12145745 Free PMC article.
Genetic association of the R620W polymorphism of protein tyrosine phosphatase PTPN22 with human SLE.
Kyogoku C, Langefeld CD, Ortmann WA, Lee A, Selby S, Carlton VE, Chang M, Ramos P, Baechler EC, Batliwalla FM, Novitzke J, Williams AH, Gillett C, Rodine P, Graham RR, Ardlie KG, Gaffney PM, Moser KL, Petri M, Begovich AB, Gregersen PK, Behrens TW. Kyogoku C, et al. Among authors: gaffney pm. Am J Hum Genet. 2004 Sep;75(3):504-7. doi: 10.1086/423790. Epub 2004 Jul 23. Am J Hum Genet. 2004. PMID: 15273934 Free PMC article.
Progress towards understanding the genetic pathogenesis of systemic lupus erythematosus.
Behrens TW, Graham RR, Kyogoku C, Baechler EC, Ramos PS, Gillett C, Bauer J, Ortmann WA, Hippen KL, Peterson E, Langefeld CD, Moser KL, Gaffney PM, Gregersen PK. Behrens TW, et al. Among authors: gaffney pm. Novartis Found Symp. 2005;267:145-60; discussion 160-4. doi: 10.1002/047002139x.ch10. Novartis Found Symp. 2005. PMID: 15999805
Familial aggregation and linkage analysis of autoantibody traits in pedigrees multiplex for systemic lupus erythematosus.
Ramos PS, Kelly JA, Gray-McGuire C, Bruner GR, Leiran AN, Meyer CM, Namjou B, Espe KJ, Ortmann WA, Reichlin M, Langefeld CD, James JA, Gaffney PM, Behrens TW, Harley JB, Moser KL. Ramos PS, et al. Among authors: gaffney pm. Genes Immun. 2006 Jul;7(5):417-32. doi: 10.1038/sj.gene.6364316. Epub 2006 Jun 15. Genes Immun. 2006. PMID: 16775618
Meta-analysis of genome-wide linkage studies of systemic lupus erythematosus.
Forabosco P, Gorman JD, Cleveland C, Kelly JA, Fisher SA, Ortmann WA, Johansson C, Johanneson B, Moser KL, Gaffney PM, Tsao BP, Cantor RM, Alarcón-Riquelme ME, Behrens TW, Harley JB, Lewis CM, Criswell LA. Forabosco P, et al. Among authors: gaffney pm. Genes Immun. 2006 Oct;7(7):609-14. doi: 10.1038/sj.gene.6364338. Epub 2006 Sep 14. Genes Immun. 2006. PMID: 16971955
221 results