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Spike and nsp6 are key determinants of SARS-CoV-2 Omicron BA.1 attenuation.
Chen DY, Chin CV, Kenney D, Tavares AH, Khan N, Conway HL, Liu G, Choudhary MC, Gertje HP, O'Connell AK, Adams S, Kotton DN, Herrmann A, Ensser A, Connor JH, Bosmann M, Li JZ, Gack MU, Baker SC, Kirchdoerfer RN, Kataria Y, Crossland NA, Douam F, Saeed M. Chen DY, et al. Among authors: gack mu. Nature. 2023 Mar;615(7950):143-150. doi: 10.1038/s41586-023-05697-2. Epub 2023 Jan 11. Nature. 2023. PMID: 36630998
Identification of a second binding site on the TRIM25 B30.2 domain.
D'Cruz AA, Kershaw NJ, Hayman TJ, Linossi EM, Chiang JJ, Wang MK, Dagley LF, Kolesnik TB, Zhang JG, Masters SL, Griffin MDW, Gack MU, Murphy JM, Nicola NA, Babon JJ, Nicholson SE. D'Cruz AA, et al. Among authors: gack mu. Biochem J. 2018 Jan 23;475(2):429-440. doi: 10.1042/BCJ20170427. Biochem J. 2018. PMID: 29259080 Free PMC article.
Mechanism of TRIM25 Catalytic Activation in the Antiviral RIG-I Pathway.
Sanchez JG, Chiang JJ, Sparrer KMJ, Alam SL, Chi M, Roganowicz MD, Sankaran B, Gack MU, Pornillos O. Sanchez JG, et al. Among authors: gack mu. Cell Rep. 2016 Aug 2;16(5):1315-1325. doi: 10.1016/j.celrep.2016.06.070. Epub 2016 Jul 14. Cell Rep. 2016. PMID: 27425606 Free PMC article.
TRIM proteins: New players in virus-induced autophagy.
Sparrer KMJ, Gack MU. Sparrer KMJ, et al. Among authors: gack mu. PLoS Pathog. 2018 Feb 1;14(2):e1006787. doi: 10.1371/journal.ppat.1006787. eCollection 2018 Feb. PLoS Pathog. 2018. PMID: 29389992 Free PMC article. No abstract available.
RIG-I works double duty.
Chan YK, Gack MU. Chan YK, et al. Among authors: gack mu. Cell Host Microbe. 2015 Mar 11;17(3):285-287. doi: 10.1016/j.chom.2015.02.014. Cell Host Microbe. 2015. PMID: 25766287 Free PMC article.
98 results