Gach K - Search Results

1

Design, synthesis and cytotoxic evaluation of 4-methylidenepyrazolidin-3-ones.

Modranka J, Jakubowski R, Różalski M, Krajewska U, Janecka A, Gach K, Pomorska D, Janecki T. Modranka J, et al. Among authors: gach k. Eur J Med Chem. 2015 Mar 6;92:565-74. doi: 10.1016/j.ejmech.2015.01.029. Epub 2015 Jan 14. Eur J Med Chem. 2015. PMID: 25602933

2

Anticancer properties of novel 4-methylene-1,2-diphenylpyrazolidin-3-ones.

Gach K, Szymański J, Pomorska D, Długosz A, Modranka J, Michalak M, Janecki T, Janecka A. Gach K, et al. Chem Biol Drug Des. 2015 Nov;86(5):961-8. doi: 10.1111/cbdd.12565. Epub 2015 Apr 21. Chem Biol Drug Des. 2015. PMID: 25832885

3

Anticancer properties of new synthetic hybrid molecules combining naphtho[2,3-b]furan-4,9-dione or benzo[f]indole-4,9-dione motif with phosphonate subunit.

Gach K, Modranka J, Szymański J, Pomorska D, Krajewska U, Mirowski M, Janecki T, Janecka A. Gach K, et al. Eur J Med Chem. 2016 Sep 14;120:51-63. doi: 10.1016/j.ejmech.2016.05.002. Epub 2016 May 3. Eur J Med Chem. 2016. PMID: 27187858

4

Combined effects of anticancer drugs and new synthetic α-methylene-δ-lactones on MCF-7 cells.

Gach K, Szymański J, Pomorska D, Długosz A, Modranka J, Janecki T, Janecka A. Gach K, et al. Tumour Biol. 2015 Aug;36(8):5971-7. doi: 10.1007/s13277-015-3273-x. Epub 2015 Mar 6. Tumour Biol. 2015. PMID: 25740060

5

Biological activity of endomorphin and [Dmt1]endomorphin analogs with six-membered proline surrogates in position 2.

Perlikowska R, Gach K, Fichna J, Toth G, Walkowiak B, do-Rego JC, Janecka A. Perlikowska R, et al. Among authors: gach k. Bioorg Med Chem. 2009 Jun 1;17(11):3789-94. doi: 10.1016/j.bmc.2009.04.046. Epub 2009 May 3. Bioorg Med Chem. 2009. PMID: 19435668

6

Comparison of anti-invasive activity of parthenolide and 3-isopropyl-2-methyl-4-methyleneisoxazolidin-5-one (MZ-6)--a new compound with α-methylene-γ-lactone motif--on two breast cancer cell lines.

Wyrębska A, Gach K, Szemraj J, Szewczyk K, Hrabec E, Koszuk J, Janecki T, Janecka A. Wyrębska A, et al. Among authors: gach k. Chem Biol Drug Des. 2012 Jan;79(1):112-20. doi: 10.1111/j.1747-0285.2011.01257.x. Epub 2011 Nov 4. Chem Biol Drug Des. 2012. PMID: 21992414

7

Effect of 2',6'-dimethyl-L-tyrosine (Dmt) on pharmacological activity of cyclic endomorphin-2 and morphiceptin analogs.

Fichna J, Perlikowska R, Wyrębska A, Gach K, Piekielna J, do-Rego JC, Toth G, Kluczyk A, Janecki T, Janecka A. Fichna J, et al. Among authors: gach k. Bioorg Med Chem. 2011 Dec 1;19(23):6977-81. doi: 10.1016/j.bmc.2011.10.040. Epub 2011 Oct 20. Bioorg Med Chem. 2011. PMID: 22047797

8

Natural and synthetic α-methylenelactones and α-methylenelactams with anticancer potential.

Janecka A, Wyrębska A, Gach K, Fichna J, Janecki T. Janecka A, et al. Among authors: gach k. Drug Discov Today. 2012 Jun;17(11-12):561-72. doi: 10.1016/j.drudis.2012.01.013. Epub 2012 Jan 28. Drug Discov Today. 2012. PMID: 22309965 Review.

9

Synthesis and opioid activity of novel 6-ketolevorphanol derivatives.

Gyulai Z, Udvardy A, Cs Bényei A, Fichna J, Gach K, Storr M, Tóth G, Antus S, Berényi S, Janecka A, Sipos A. Gyulai Z, et al. Among authors: gach k. Med Chem. 2013 Feb;9(1):1-10. doi: 10.2174/157340613804488323. Med Chem. 2013. PMID: 22741803

10

Apoptosis-mediated cytotoxic effects of parthenolide and the new synthetic analog MZ-6 on two breast cancer cell lines.

Wyrębska A, Szymański J, Gach K, Piekielna J, Koszuk J, Janecki T, Janecka A. Wyrębska A, et al. Among authors: gach k. Mol Biol Rep. 2013 Feb;40(2):1655-63. doi: 10.1007/s11033-012-2215-6. Epub 2012 Oct 14. Mol Biol Rep. 2013. PMID: 23065294 Free PMC article.

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