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Upregulation of C/EBPα Inhibits Suppressive Activity of Myeloid Cells and Potentiates Antitumor Response in Mice and Patients with Cancer.
Hashimoto A, Sarker D, Reebye V, Jarvis S, Sodergren MH, Kossenkov A, Sanseviero E, Raulf N, Vasara J, Andrikakou P, Meyer T, Huang KW, Plummer R, Chee CE, Spalding D, Pai M, Khan S, Pinato DJ, Sharma R, Basu B, Palmer D, Ma YT, Evans J, Habib R, Martirosyan A, Elasri N, Reynaud A, Rossi JJ, Cobbold M, Habib NA, Gabrilovich DI. Hashimoto A, et al. Among authors: gabrilovich di. Clin Cancer Res. 2021 Nov 1;27(21):5961-5978. doi: 10.1158/1078-0432.CCR-21-0986. Epub 2021 Aug 18. Clin Cancer Res. 2021. PMID: 34407972 Free PMC article. Clinical Trial.
Anti-inflammatory triterpenoid blocks immune suppressive function of MDSCs and improves immune response in cancer.
Nagaraj S, Youn JI, Weber H, Iclozan C, Lu L, Cotter MJ, Meyer C, Becerra CR, Fishman M, Antonia S, Sporn MB, Liby KT, Rawal B, Lee JH, Gabrilovich DI. Nagaraj S, et al. Among authors: gabrilovich di. Clin Cancer Res. 2010 Mar 15;16(6):1812-23. doi: 10.1158/1078-0432.CCR-09-3272. Epub 2010 Mar 9. Clin Cancer Res. 2010. PMID: 20215551 Free PMC article.
Myeloid-derived suppressor cells in the development of lung cancer.
Ortiz ML, Lu L, Ramachandran I, Gabrilovich DI. Ortiz ML, et al. Among authors: gabrilovich di. Cancer Immunol Res. 2014 Jan;2(1):50-8. doi: 10.1158/2326-6066.CIR-13-0129. Epub 2013 Oct 18. Cancer Immunol Res. 2014. PMID: 24778162 Free PMC article.
Selective Targeting of Myeloid-Derived Suppressor Cells in Cancer Patients Using DS-8273a, an Agonistic TRAIL-R2 Antibody.
Dominguez GA, Condamine T, Mony S, Hashimoto A, Wang F, Liu Q, Forero A, Bendell J, Witt R, Hockstein N, Kumar P, Gabrilovich DI. Dominguez GA, et al. Among authors: gabrilovich di. Clin Cancer Res. 2017 Jun 15;23(12):2942-2950. doi: 10.1158/1078-0432.CCR-16-1784. Epub 2016 Dec 13. Clin Cancer Res. 2017. PMID: 27965309 Free PMC article. Clinical Trial.
Myeloid-Derived Suppressor Cells.
Gabrilovich DI. Gabrilovich DI. Cancer Immunol Res. 2017 Jan;5(1):3-8. doi: 10.1158/2326-6066.CIR-16-0297. Cancer Immunol Res. 2017. PMID: 28052991 Free PMC article. Review.
Lectin-type oxidized LDL receptor-1 distinguishes population of human polymorphonuclear myeloid-derived suppressor cells in cancer patients.
Condamine T, Dominguez GA, Youn JI, Kossenkov AV, Mony S, Alicea-Torres K, Tcyganov E, Hashimoto A, Nefedova Y, Lin C, Partlova S, Garfall A, Vogl DT, Xu X, Knight SC, Malietzis G, Lee GH, Eruslanov E, Albelda SM, Wang X, Mehta JL, Bewtra M, Rustgi A, Hockstein N, Witt R, Masters G, Nam B, Smirnov D, Sepulveda MA, Gabrilovich DI. Condamine T, et al. Among authors: gabrilovich di. Sci Immunol. 2016 Aug;1(2):aaf8943. doi: 10.1126/sciimmunol.aaf8943. Epub 2016 Aug 5. Sci Immunol. 2016. PMID: 28417112 Free PMC article.
267 results