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Manipulating the pH response of 2,3-diaminopropionic acid rich peptides to mediate highly effective gene silencing with low-toxicity.
Abbate V, Liang W, Patel J, Lan Y, Capriotti L, Iacobucci V, Bui TT, Chaudhuri P, Kudsiova L, Vermeer LS, Chan PF, Kong X, Drake AF, Lam JK, Bansal SS, Mason AJ. Abbate V, et al. J Control Release. 2013 Dec 28;172(3):929-38. doi: 10.1016/j.jconrel.2013.09.033. Epub 2013 Oct 18. J Control Release. 2013. PMID: 24144917 Free PMC article.
Conformational flexibility determines selectivity and antibacterial, antiplasmodial, and anticancer potency of cationic α-helical peptides.
Vermeer LS, Lan Y, Abbate V, Ruh E, Bui TT, Wilkinson LJ, Kanno T, Jumagulova E, Kozlowska J, Patel J, McIntyre CA, Yam WC, Siu G, Atkinson RA, Lam JK, Bansal SS, Drake AF, Mitchell GH, Mason AJ. Vermeer LS, et al. J Biol Chem. 2012 Oct 5;287(41):34120-33. doi: 10.1074/jbc.M112.359067. Epub 2012 Aug 6. J Biol Chem. 2012. PMID: 22869378 Free PMC article.
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