Gütschow M - Search Results

1

Matriptase-2: monitoring and inhibiting its proteolytic activity.

Gitlin-Domagalska A, Mangold M, Dębowski D, Ptaszyńska N, Łęgowska A, Gütschow M, Rolka K. Gitlin-Domagalska A, et al. Among authors: gutschow m. Future Med Chem. 2018 Dec;10(23):2745-2761. doi: 10.4155/fmc-2018-0346. Epub 2018 Dec 6. Future Med Chem. 2018. PMID: 30518272 Review.

2

Identification of the first low-molecular-weight inhibitors of matriptase-2.

Sisay MT, Steinmetzer T, Stirnberg M, Maurer E, Hammami M, Bajorath J, Gütschow M. Sisay MT, et al. Among authors: gutschow m. J Med Chem. 2010 Aug 12;53(15):5523-35. doi: 10.1021/jm100183e. J Med Chem. 2010. PMID: 20684597

3

Matriptase-2 (TMPRSS6) is directly up-regulated by hypoxia inducible factor-1: identification of a hypoxia-responsive element in the TMPRSS6 promoter region.

Maurer E, Gütschow M, Stirnberg M. Maurer E, et al. Among authors: gutschow m. Biol Chem. 2012 May;393(6):535-40. doi: 10.1515/hsz-2011-0221. Biol Chem. 2012. PMID: 22628316

4

Selective nitrile inhibitors to modulate the proteolytic synergism of cathepsins S and F.

Frizler M, Schmitz J, Schulz-Fincke AC, Gütschow M. Frizler M, et al. Among authors: gutschow m. J Med Chem. 2012 Jun 28;55(12):5982-6. doi: 10.1021/jm300734k. Epub 2012 Jun 20. J Med Chem. 2012. PMID: 22686657

5

Active site mapping of trypsin, thrombin and matriptase-2 by sulfamoyl benzamidines.

Dosa S, Stirnberg M, Lülsdorff V, Häußler D, Maurer E, Gütschow M. Dosa S, et al. Among authors: gutschow m. Bioorg Med Chem. 2012 Nov 1;20(21):6489-505. doi: 10.1016/j.bmc.2012.08.042. Epub 2012 Sep 5. Bioorg Med Chem. 2012. PMID: 23026080

6

Hepatocyte growth factor activator inhibitor type 2 (HAI-2) modulates hepcidin expression by inhibiting the cell surface protease matriptase-2.

Maurer E, Gütschow M, Stirnberg M. Maurer E, et al. Among authors: gutschow m. Biochem J. 2013 Mar 15;450(3):583-93. doi: 10.1042/BJ20121518. Biochem J. 2013. PMID: 23293962

7

Substrate specificity of human matriptase-2.

Wysocka M, Gruba N, Miecznikowska A, Popow-Stellmaszyk J, Gütschow M, Stirnberg M, Furtmann N, Bajorath J, Lesner A, Rolka K. Wysocka M, et al. Among authors: gutschow m. Biochimie. 2014 Feb;97:121-7. doi: 10.1016/j.biochi.2013.10.001. Epub 2013 Oct 22. Biochimie. 2014. PMID: 24161741

8

Inhibitors of Matriptase-2 Based on the Trypsin Inhibitor SFTI-1.

Gitlin A, Dębowski D, Karna N, Łęgowska A, Stirnberg M, Gütschow M, Rolka K. Gitlin A, et al. Among authors: gutschow m. Chembiochem. 2015 Jul 27;16(11):1601-7. doi: 10.1002/cbic.201500200. Epub 2015 Jun 19. Chembiochem. 2015. PMID: 25999208

9

Metalloprotease meprin β is activated by transmembrane serine protease matriptase-2 at the cell surface thereby enhancing APP shedding.

Jäckle F, Schmidt F, Wichert R, Arnold P, Prox J, Mangold M, Ohler A, Pietrzik CU, Koudelka T, Tholey A, Gütschow M, Stirnberg M, Becker-Pauly C. Jäckle F, et al. Among authors: gutschow m. Biochem J. 2015 Aug 15;470(1):91-103. doi: 10.1042/BJ20141417. Epub 2015 Jun 15. Biochem J. 2015. PMID: 26251449

10

The intact Kunitz domain protects the amyloid precursor protein from being processed by matriptase-2.

Beckmann AM, Glebov K, Walter J, Merkel O, Mangold M, Schmidt F, Becker-Pauly C, Gütschow M, Stirnberg M. Beckmann AM, et al. Among authors: gutschow m. Biol Chem. 2016 Aug 1;397(8):777-90. doi: 10.1515/hsz-2015-0263. Biol Chem. 2016. PMID: 27078672

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

248 results

Search Page