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Design, synthesis, and testing toward a 57-codon genome.
Ostrov N, Landon M, Guell M, Kuznetsov G, Teramoto J, Cervantes N, Zhou M, Singh K, Napolitano MG, Moosburner M, Shrock E, Pruitt BW, Conway N, Goodman DB, Gardner CL, Tyree G, Gonzales A, Wanner BL, Norville JE, Lajoie MJ, Church GM. Ostrov N, et al. Among authors: guell m. Science. 2016 Aug 19;353(6301):819-22. doi: 10.1126/science.aaf3639. Science. 2016. PMID: 27540174
RNA-guided human genome engineering via Cas9.
Mali P, Yang L, Esvelt KM, Aach J, Guell M, DiCarlo JE, Norville JE, Church GM. Mali P, et al. Among authors: guell m. Science. 2013 Feb 15;339(6121):823-6. doi: 10.1126/science.1232033. Epub 2013 Jan 3. Science. 2013. PMID: 23287722 Free PMC article.
Proteome organization in a genome-reduced bacterium.
Kühner S, van Noort V, Betts MJ, Leo-Macias A, Batisse C, Rode M, Yamada T, Maier T, Bader S, Beltran-Alvarez P, Castaño-Diez D, Chen WH, Devos D, Güell M, Norambuena T, Racke I, Rybin V, Schmidt A, Yus E, Aebersold R, Herrmann R, Böttcher B, Frangakis AS, Russell RB, Serrano L, Bork P, Gavin AC. Kühner S, et al. Among authors: guell m. Science. 2009 Nov 27;326(5957):1235-40. doi: 10.1126/science.1176343. Science. 2009. PMID: 19965468
Genome-wide inactivation of porcine endogenous retroviruses (PERVs).
Yang L, Güell M, Niu D, George H, Lesha E, Grishin D, Aach J, Shrock E, Xu W, Poci J, Cortazio R, Wilkinson RA, Fishman JA, Church G. Yang L, et al. Among authors: guell m. Science. 2015 Nov 27;350(6264):1101-4. doi: 10.1126/science.aad1191. Epub 2015 Oct 11. Science. 2015. PMID: 26456528
91 results